[HTML][HTML] Teriparatide (human parathyroid hormone (1–34)) inhibits osteogenic vascular calcification in diabetic low density lipoprotein receptor-deficient mice
JS Shao, SL Cheng, N Charlton-Kachigian… - Journal of Biological …, 2003 - ASBMB
Cardiovascular calcification is a common consequence of diabetes. High fat diets induce
diabetes and arterial calcification in male low density lipoprotein receptor (LDLR)–/–mice;
calcification occurs via Msx2 signaling that promotes the osteogenic differentiation of arterial
myofibroblasts. We studied regulation of arterial osteogenesis by human parathyroid
hormone (PTH)(1–34)(also called teriparatide) in LDLR–/–mice fed diabetogenic diets for 4
weeks. LDLR–/–mice were treated with vehicle or 0.4 mg/kg of PTH (1–34) subcutaneously …
diabetes and arterial calcification in male low density lipoprotein receptor (LDLR)–/–mice;
calcification occurs via Msx2 signaling that promotes the osteogenic differentiation of arterial
myofibroblasts. We studied regulation of arterial osteogenesis by human parathyroid
hormone (PTH)(1–34)(also called teriparatide) in LDLR–/–mice fed diabetogenic diets for 4
weeks. LDLR–/–mice were treated with vehicle or 0.4 mg/kg of PTH (1–34) subcutaneously …