Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair.

JM Wozney, V Rosen - Clinical Orthopaedics and Related …, 1998 - journals.lww.com
The bone morphogenetic proteins are secreted signalling molecules that belong to the
transforming growth factor [beta] family of growth and differentiation factors. Individual bone
morphogenetic proteins are prominent at many sites during embryogenesis and are likely to
be key regulators of early development and organogenesis. In vertebrates, one of the
functions of bone morphogenetic like proteins is to induce formation of bone, cartilage, and
connective tissues associated with the skeleton. This osteoinductive ability has led to the …