Microfibrils are a major component of the mesangial matrix in the glomerulus of the rat kidney

P Mundel, M Elger, T Sakai, W Kriz - Cell and tissue research, 1988 - Springer
P Mundel, M Elger, T Sakai, W Kriz
Cell and tissue research, 1988Springer
The mesangial matrix of the rat glomerulus was studied by transmission electron microscopy
in specimens preserved by a modified technique, which avoids osmium tetroxide but uses
tannic acid as a contrasting agent. It can be demonstrated that microfibrils are a major
component of the normal glomerular mesangial matrix. They are non-branching tubular
structures with a hollow centre, an undefined length and a thickness of∼ 15 nm. Microfibrils
make up a dense fibrillar network interconnecting mesangial cells and glomerular basement …
Summary
The mesangial matrix of the rat glomerulus was studied by transmission electron microscopy in specimens preserved by a modified technique, which avoids osmium tetroxide but uses tannic acid as a contrasting agent. It can be demonstrated that microfibrils are a major component of the normal glomerular mesangial matrix. They are non-branching tubular structures with a hollow centre, an undefined length and a thickness of ∼15 nm. Microfibrils make up a dense fibrillar network interconnecting mesangial cells and glomerular basement membrane.
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