[HTML][HTML] Interaction between Not1p, a component of the Ccr4-not complex, a global regulator of transcription, and Dhh1p, a putative RNA helicase
L Maillet, MA Collart - Journal of Biological Chemistry, 2002 - ASBMB
The Ccr4-Not complex is a global regulator of transcription that affects genes positively and
negatively and is thought to regulate transcription factor IID function. Two components of this
complex, Caf1p and Ccr4p, are directly involved in mRNA deadenylation, and Caf1p is
associated with Dhh1p, a putative RNA helicase thought to be a component of the
decapping complex. In this work, we tried to determine whether Dhh1p might interact with
the Ccr4-Not complex. We found that, first, not mutations displayed severe synthetic …
negatively and is thought to regulate transcription factor IID function. Two components of this
complex, Caf1p and Ccr4p, are directly involved in mRNA deadenylation, and Caf1p is
associated with Dhh1p, a putative RNA helicase thought to be a component of the
decapping complex. In this work, we tried to determine whether Dhh1p might interact with
the Ccr4-Not complex. We found that, first, not mutations displayed severe synthetic …