[HTML][HTML] Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain

Y Jiang, B Vaessen, T Lenvik, M Blackstad… - Experimental …, 2002 - Elsevier
OBJECTIVE: Recent studies have shown that cells from bone marrow (BM), muscle, and
brain may have greater plasticity than previously known. We have identified multipotent
adult progenitor cells (MAPC) in postnatal human and rodent BM that copurify with
mesenchymal stem cells (MSC). BM MAPC proliferate without senescence and differentiate
into mesodermal, neuroectodermal, and endodermal cell types. We hypothesized that cells
with characteristics similar to BM MAPC can be selected and cultured from tissues other than …