The portal area is the 'main entrance'and one of the two main exits of the liver lobule.
Through the main entrance portal and arterial blood reach the liver sinusoids. Through the
exit the bile flows towards the duodenum. The three main structures, portal vein and artery
with their own wall (and vascular smooth muscle cells) and bile duct with its basal
membrane, are surrounded by loose myofibroblasts and by the first layer of hepatocytes and
non-parenchymal cells. Chronic diseases of the liver can lead to development of liver …