Towarfs a viral etiology for paget's disease of bone
A Rebel, M Basle, A Pouplard, K Malkani… - Metabolic Bone Disease …, 1981 - Elsevier
The etiology of Paget's disease of bone has long remained obscure. The recent discovery in
electron microscopy of specific Inclusions In the cytoplasm and nuclei of osteociasts in tissue
from patients with Paget's bone disease has been the starting point of investigations into a
possible viral origin. The inclusions, made up of microcylinders, described by several
authors as being found only In osteoclasts in Paget's bone disease, present a close
morphological analogy with nucleocapsids of paramyxovirus of the measles group …
electron microscopy of specific Inclusions In the cytoplasm and nuclei of osteociasts in tissue
from patients with Paget's bone disease has been the starting point of investigations into a
possible viral origin. The inclusions, made up of microcylinders, described by several
authors as being found only In osteoclasts in Paget's bone disease, present a close
morphological analogy with nucleocapsids of paramyxovirus of the measles group …