[27] Design, production, safety, evaluation, and clinical applications of nonprimate lentiviral vectors
JB Rohll, KA Mitrophanous, E Martin-Rendon… - Methods in …, 2002 - Elsevier
Lentivirus-based vectors are ideal tools for gene transfer because of their ability to stably
integrate into the genome of dividing and nondividing cells and to mediate long-term gene
expression. 1-4 The majority of research has been carded out using vectors derived from
human immunodeficiency virus, type 1 (HIV-1), and has been greatly facilitated by the
wealth of information and reagents that have been accumulated on this virus since its
recognition as the causal agent of AIDS in 1984. However, vector systems based on other …
integrate into the genome of dividing and nondividing cells and to mediate long-term gene
expression. 1-4 The majority of research has been carded out using vectors derived from
human immunodeficiency virus, type 1 (HIV-1), and has been greatly facilitated by the
wealth of information and reagents that have been accumulated on this virus since its
recognition as the causal agent of AIDS in 1984. However, vector systems based on other …