Dapsone and sulfones in dermatology: overview and update
YI Zhu, MJ Stiller - Journal of the American Academy of dermatology, 2001 - Elsevier
In their 60-year history, dapsone and the sulfones have been used as both antibacterial and
anti-inflammatory agents. Dapsone has been used successfully to treat a range of
dermatologic disorders, most successfully those characterized by abnormal neutrophil and
eosinophil accumulation. This article reviews and updates the chemistry, pharmacokinetics,
clinical application, mechanism of action, adverse effects, and drug interactions of dapsone
and the sulfones in dermatology.(J Am Acad Dermatol 2001; 45: 420-34.)
anti-inflammatory agents. Dapsone has been used successfully to treat a range of
dermatologic disorders, most successfully those characterized by abnormal neutrophil and
eosinophil accumulation. This article reviews and updates the chemistry, pharmacokinetics,
clinical application, mechanism of action, adverse effects, and drug interactions of dapsone
and the sulfones in dermatology.(J Am Acad Dermatol 2001; 45: 420-34.)
