The fine structure of type II muscle fiber atrophy
JR Mendell, WK Engel - Neurology, 1971 - AAN Enterprises
JR Mendell, WK Engel
Neurology, 1971•AAN EnterprisesMETHODS Muscle biopsies were obtained from the left vastus lateralis (Case I), right vastus
lateralis (Case 3), and left biceps (Cases 2 and 4). Specimens for histochemistry were frozen
immediately in isopentane cooled in liquid nitrogen and subsequently sectioned at 10 p in a
cryostat. A battery of 17 histochemical reactions was used as detailed elsewhere. 3 Fiber
typing was done on sections stained for myofibrillar adenosine triphosphatase (ATPase) at a
pH of 9.4899 and confirmed with other reactions, especially the one for EDTA-low pH …
lateralis (Case 3), and left biceps (Cases 2 and 4). Specimens for histochemistry were frozen
immediately in isopentane cooled in liquid nitrogen and subsequently sectioned at 10 p in a
cryostat. A battery of 17 histochemical reactions was used as detailed elsewhere. 3 Fiber
typing was done on sections stained for myofibrillar adenosine triphosphatase (ATPase) at a
pH of 9.4899 and confirmed with other reactions, especially the one for EDTA-low pH …
METHODS
Muscle biopsies were obtained from the left vastus lateralis (Case I), right vastus lateralis (Case 3), and left biceps (Cases 2 and 4). Specimens for histochemistry were frozen immediately in isopentane cooled in liquid nitrogen and subsequently sectioned at 10 p in a cryostat. A battery of 17 histochemical reactions was used as detailed elsewhere. 3 Fiber typing was done on sections stained for myofibrillar adenosine triphosphatase (ATPase) at a pH of 9.4899 and confirmed with other reactions, especially the one for EDTA-low pH-activated ATPase. 10 Adjacent fascicles of mus-
American Academy of Neurology