Central administration of thyrotropin releasing hormone (TRH) and related peptides inhibits feeding behavior in the Siberian hamster

CA Steward, TL Horan, S Schuhler, GW Bennett… - …, 2003 - journals.lww.com
Centrally acting thyrotropin releasing hormone (TRH), independent of endocrine action, has
been shown to regulate several metabolic and behavioral parameters in rats, including food
intake and locomotor activity. The present study investigated and compared the effects of
central TRH on feeding behavior in Siberian hamsters exposed to long (LP) or short (SP)
photoperiods, which induce natural physiological states of obesity and leanness
respectively. The effects of two TRH analogues, RX77368 (a metabolically stable TRH …