Picornavirus RNA translation: roles for cellular proteins
GJ Belsham, N Sonenberg - Trends in microbiology, 2000 - cell.com
Trends in microbiology, 2000•cell.com
Picornavirus RNA is translated within cells even when cellular cap-dependent protein
synthesis is blocked. The efficiency of recognition of the viral RNA by the translational
apparatus can determine viral tropism. The roles of cellular translation-initiation factors and
other RNA-binding proteins in viral RNA-mediated protein synthesis are discussed.
synthesis is blocked. The efficiency of recognition of the viral RNA by the translational
apparatus can determine viral tropism. The roles of cellular translation-initiation factors and
other RNA-binding proteins in viral RNA-mediated protein synthesis are discussed.
Abstract
Picornavirus RNA is translated within cells even when cellular cap-dependent protein synthesis is blocked. The efficiency of recognition of the viral RNA by the translational apparatus can determine viral tropism. The roles of cellular translation-initiation factors and other RNA-binding proteins in viral RNA-mediated protein synthesis are discussed.
cell.com