Interpretation of the cross-reactivity of anti-DNA antibodies with cell surface proteins: the role of cell surface histones
T Kubota, Y Kanai, N Miyasaka - Immunology letters, 1990 - Elsevier
The putative cross-reaction of anti-DNA antibodies with “lupus-associated membrane
proteins (LAMP)” on the surface of intact Raji cells was examined by sodium dodecyl
sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblotting analyses.
Cell surface proteins of 14, 17, 18, 33 and 34 kDa were detected by monoclonal anti-double-
stranded (ds) DNA antibodies and the sera of patients with systemic lupus erythematosus
(SLE) in active states, but were not detected by the sera of SLE patients in inactive states …
proteins (LAMP)” on the surface of intact Raji cells was examined by sodium dodecyl
sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblotting analyses.
Cell surface proteins of 14, 17, 18, 33 and 34 kDa were detected by monoclonal anti-double-
stranded (ds) DNA antibodies and the sera of patients with systemic lupus erythematosus
(SLE) in active states, but were not detected by the sera of SLE patients in inactive states …
