Spectrum of sinus node dysfunction in two siblings

A Nordenberg, PJ Varghese, EW Nugent - American Heart Journal, 1976 - Elsevier
A Nordenberg, PJ Varghese, EW Nugent
American Heart Journal, 1976Elsevier
Summary Two siblings, ages 14 and 23, with various features of sinus node dysfunction
have been reported. Sinus bradycardia was the presenting feature in both patients. During
the follow-up period both patients developed various types of ectopic rhythms which
increased with exercise. One of them developed “silent atrium” at the age of 23 and had
cerebral embolus as a complication. The other patient had frequent syncopal episodes and
had to be treated with a combination of electronic pacemaker and antiarrhythmic drugs.
Summary
Two siblings, ages 14 and 23, with various features of sinus node dysfunction have been reported. Sinus bradycardia was the presenting feature in both patients. During the follow-up period both patients developed various types of ectopic rhythms which increased with exercise. One of them developed “silent atrium” at the age of 23 and had cerebral embolus as a complication. The other patient had frequent syncopal episodes and had to be treated with a combination of electronic pacemaker and antiarrhythmic drugs.
Elsevier