Localization of ROMK channels in the rat kidney.
PA Mennitt, JB Wade, CA Ecelbarger… - Journal of the …, 1997 - journals.lww.com
Renal potassium secretion occurs in the distal segments of the nephron through apically
located secretory potassium (SK) channels. SK may correspond to the ROMK channels
cloned from rat kidney. In this study, the localization of ROMK at the cellular level in the rat
kidney was examined using an affinity-purified polyclonal antibody raised against a C-
terminal peptide of ROMK. The specificity of the antibody was demonstrated by immunoblots
of membranes of Xenopus oocytes expressing ROMK2. Immunoblots of homogenates from …
located secretory potassium (SK) channels. SK may correspond to the ROMK channels
cloned from rat kidney. In this study, the localization of ROMK at the cellular level in the rat
kidney was examined using an affinity-purified polyclonal antibody raised against a C-
terminal peptide of ROMK. The specificity of the antibody was demonstrated by immunoblots
of membranes of Xenopus oocytes expressing ROMK2. Immunoblots of homogenates from …