Our understanding of the regulation of appetite and energy balance has advanced
significantly over the past decade as several peptides, centrally or peripherally expressed,
have been characterized and shown to profoundly influence food intake and energy
expenditure. 1The growing number of putative appetite-regulating neuropeptides includes
peptides that are orexigenic (appetite-stimulating) signals and anorectic peptides.
Neuropeptide Y (NPY), melanin concentrating hormone (MCH), orexins A and B, galanin …