The proopiomelanocortin (POMC)-derived peptides are important regulators in a number of
central nervous system pathways especially as they relate to food intake as well as
metabolic and autonomic responses. In this study, we investigated the sympathetic nervous
and cardiovascular responses to intracerebroventricular (icv) administration of alpha
melanocyte stimulating hormone (αMSH), β-endorphin (β-END) and adrenal corticotrophic
hormone (ACTH) alone or in the presence of a melanocortin antagonist, or an opioid …