Publisher Summary This chapter provides an overview of transglutaminases, which are
enzymes that catalyze the calcium-dependent acyl transfer reaction in which γ-carboxamide
groups of peptide-bound glutamine residues serve as acyl donors. These enzymes display
specificity differences that are expressed as variations in reactivity towards glutamine
residues and that are predicated by the sequences of amino acid residues surrounding the
glutamines. The specificity of each of the transglutaminases towards acceptor substrates is …