[HTML][HTML] Definition of the sites of interaction between the protein tyrosine phosphatase SHP-1 and CD22
J Blasioli, S Paust, ML Thomas - Journal of Biological Chemistry, 1999 - ASBMB
CD22 phosphorylation is an early event of B cell antigen receptor engagement and results
in the recruitment of the negative regulatory tyrosine phosphatase, SHP-1. Peptides
representing the potential phosphorylation sites within the cytoplasmic domain of CD22
have been used to stimulate SHP-1 catalytic activity and to inhibit the binding of SHP-1 to
CD22 (Doody, G., Justement, L., Delibrias, C., Matthews, R., Lin, J., Thomas, M., and Fearon,
D.(1995) Science 269, 242–244). However, the sites of phosphorylation within the …
in the recruitment of the negative regulatory tyrosine phosphatase, SHP-1. Peptides
representing the potential phosphorylation sites within the cytoplasmic domain of CD22
have been used to stimulate SHP-1 catalytic activity and to inhibit the binding of SHP-1 to
CD22 (Doody, G., Justement, L., Delibrias, C., Matthews, R., Lin, J., Thomas, M., and Fearon,
D.(1995) Science 269, 242–244). However, the sites of phosphorylation within the …