Cytokine profile of viral and autoimmune chronic active hepatitis

A Al-Wabel, M Al-Janadi, S Raziuddin - Journal of allergy and clinical …, 1993 - Elsevier
Background: Patients with hepatitis have multiple immunologic abnormalities, which may be
related to cytokine production. Methods: We examined the in vitro production of interleukins
(IL-2, IL-4, IL-6), tumor necrosis factor-α (TNF-α), and interferon-γ (IFN-γ) in purified
peripheral blood mononuclear cells (PBMCs) of patients with hepatitis B virus positive
(HBV), acute viral hepatitis (A-HBV), HBV+ chronic active hepatitis (HBV-CAH), and
autoimmune-type chronic active hepatitis (AI-ACH). Results: IFN-γ and TNF-α production …