Assessment of myeloperoxidase activity in whole rat kidney

LM Hillegass, DE Griswold, B Brickson… - Journal of …, 1990 - Elsevier
A method to quantitate myeloperoxidase (MPO) activity from rat whole kidney is described.
Polymorphonuclear leukocyte (PMN) infiltration into tissue is a hallmark of acute
inflammation. Historically, the degree of inflammation has been quantified by the
identification and enumeration of PMNs histologically or by some other means. More
recently, the enzyme activity of MPO, a marker enzyme for PMN, and freshly emigrated
monocytes in many inflamed tissues has replaced these methods. The kidney, however, has …