[HTML][HTML] Regulation of mRNA Expression in Macrophages afterYersinia enterocolitica Infection: ROLE OF DIFFERENT Yop EFFECTORS

N Sauvonnet, B Pradet-Balade, JA Garcia-Sanz… - Journal of Biological …, 2002 - ASBMB
The Yop virulon, which comprises a complete type III secretion system and secreted
proteins, allows bacteria from the genus Yersinia to resist the nonspecific immune response
of the host. This virulon, which is encoded by a plasmid called pYV in Yersinia enterocolitica,
enables extracellular bacteria to inject six Yop effectors (YopE,-H,-T,-O,-P,-M) into the host
cell. To investigate the role of YopP, YopM, and the other pYV-encoded factors on the
expression of the host cell genes, we characterized the transcriptome alterations in infected …