Comparison of the abilities ofSalmonella typhimurium rpoS, aroAandrpoS aroAstrains to elicit humoral immune responses in BALB/c mice and to cause lethal infection …

C Coynault, F Norel - Microbial pathogenesis, 1999 - Elsevier
Salmonella typhimurium rpoSandrpoS aroAmutants are effective live vaccines in the murine
model of salmonellosis (Coynaultet al., Mol. Microbiol. 1996; 22: 149–60). Here, we further
investigate the characteristics of these vaccines. The systemic humoral response induced
byS. typhimurium rpoS, aroAandrpoS aroAvaccine candidates againstS. typhimuriumLPS
was studied by ELISA. In BALB/c mice, therpoS aroAstrain induced a systemic anti-LPS
humoral response similar to that induced by therpoSandaroAstrains. The virulence …