Role of prolactin in developmental differentiation of hypophysiotropic tuberoinfundibular dopaminergic neurons
CJ Phelps, MI Romero, DL Hurley - Proceedings of the 1993 Laurentian …, 1995 - Elsevier
Publisher Summary This chapter describes the studies that evaluate whether the dopamine
(DA) deficiency develops in the postnatal differentiation of TIDA neurons in Ames dwarf
hypothalamus and the effect of PRL on that differentiation. In mice, dwarf and normal brains
were assessed from seven days of age through adulthood for hypothalamic DA levels and
TIDA neuron number; the effect of PRL replacement at an identified critical period was
compared with that in adults. A12 DA neurons in dwarfs are comparable to those of normal …
(DA) deficiency develops in the postnatal differentiation of TIDA neurons in Ames dwarf
hypothalamus and the effect of PRL on that differentiation. In mice, dwarf and normal brains
were assessed from seven days of age through adulthood for hypothalamic DA levels and
TIDA neuron number; the effect of PRL replacement at an identified critical period was
compared with that in adults. A12 DA neurons in dwarfs are comparable to those of normal …
