Expression of proliferating cell nuclear antigen (PCNA) in the adult and developing mouse nervous system
H Ino, T Chiba - Molecular brain research, 2000 - Elsevier
Proliferating cell nuclear antigen (PCNA) is essential for the function of DNA polymerases δ
and ϵ. Because proliferating cell nuclear antigen is required for DNA replication and repair,
PCNA is abundantly expressed in proliferating cells. Interestingly, PCNA mRNA has also
been detected in the adult mouse brain by Northern blot analysis. In this study, two
monoclonal antibodies against PCNA, PC10 and 19F4, were used for Western blot analysis.
Monoclonal antibody PC10, but not 19F4, detected a band in the adult mouse brain extract …
and ϵ. Because proliferating cell nuclear antigen is required for DNA replication and repair,
PCNA is abundantly expressed in proliferating cells. Interestingly, PCNA mRNA has also
been detected in the adult mouse brain by Northern blot analysis. In this study, two
monoclonal antibodies against PCNA, PC10 and 19F4, were used for Western blot analysis.
Monoclonal antibody PC10, but not 19F4, detected a band in the adult mouse brain extract …
