• Five juvenile diabetics had vitiligo. In two children, the vitiligo preceded the onset of
diabetes. Four of the five patients had thyroid, adrenal, or gastric antibodies or a
combination of these. In three children HLA-B8 antigens were detected, and one additional
patient had HLA-Bw15. Of eight nondiabetic children with vitiligo, one had abnormal glucose
tolerance. To the evidence supporting an autoimmune form of diabetes mellitus we add
another observation: the association of insulindependent diabetes and childhood …