DNA sequence and expression of the B95-8 Epstein—Barr virus genome

R Baer, AT Bankier, MD Biggin, PL Deininger… - Nature, 1984 - nature.com
R Baer, AT Bankier, MD Biggin, PL Deininger, PJ Farrell, TJ Gibson, G Hatfull, GS Hudson…
Nature, 1984nature.com
Abstract The complete (172,282 base pairs) nucleotide sequence of the B95-8 strain of
Epstein–Barr virus has been established using the dideoxynucleotide/M13 sequencing
procedure. Many RNA polymerase II promoters have been mapped and the mRNAs from
these promoters have been assigned to the latent or early/late productive virus cycles. Likely
protein-coding regions have been identified and three of these have been shown to encode
a ribonucleotide reductase, a DNA polymerase and two surface glycoproteins.
Abstract
The complete (172,282 base pairs) nucleotide sequence of the B95-8 strain of Epstein–Barr virus has been established using the dideoxynucleotide/M13 sequencing procedure. Many RNA polymerase II promoters have been mapped and the mRNAs from these promoters have been assigned to the latent or early/late productive virus cycles. Likely protein-coding regions have been identified and three of these have been shown to encode a ribonucleotide reductase, a DNA polymerase and two surface glycoproteins.
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