The cardiac toxicity of anabolic steroids

ML Sullivan, CM Martinez, P Gennis… - Progress in cardiovascular …, 1998 - Elsevier
Anabolic steroids are synthetic derivatives of testosterone that were developed as adjunct
therapy for a variety of medical conditions. Today they are most commonly used to enhance
athletic performance and muscular development. Both illicit and medically indicated
anabolic steroid use have been temporally associated with many subsequent defects within
each of the body systems. Testosterone is the preferred ligand of the human androgen
receptor in the myocardium and directly modulates transcription, translation, and enzyme …