Triglyceride synthesis: insights from the cloning of diacylglycerol acyltransferase
RV Farese Jr, S Cases, SJ Smith - Current opinion in lipidology, 2000 - journals.lww.com
RV Farese Jr, S Cases, SJ Smith
Current opinion in lipidology, 2000•journals.lww.comAlthough the biochemistry of triglyceride synthesis has been studied for decades, an
understanding of the molecular processes involved has been lacking. The recent cloning of
a gene encoding acyl coenzyme A: diacylglycerol acyltransferase, an enzyme that catalyses
the final step in triglyceride synthesis, has opened this area to molecular investigation and
has begun to provide new insights into triglyceride metabolism.
understanding of the molecular processes involved has been lacking. The recent cloning of
a gene encoding acyl coenzyme A: diacylglycerol acyltransferase, an enzyme that catalyses
the final step in triglyceride synthesis, has opened this area to molecular investigation and
has begun to provide new insights into triglyceride metabolism.
Abstract
Although the biochemistry of triglyceride synthesis has been studied for decades, an understanding of the molecular processes involved has been lacking. The recent cloning of a gene encoding acyl coenzyme A: diacylglycerol acyltransferase, an enzyme that catalyses the final step in triglyceride synthesis, has opened this area to molecular investigation and has begun to provide new insights into triglyceride metabolism.
Lippincott Williams & Wilkins