Three distinct keratinocyte subtypes identified in human oral epithelium by their patterns of keratin expression in culture and in xenografts

K Lindberg, JG Rheinwald - Differentiation, 1990 - Elsevier
We have characterized the cells that form the human oral epithelia by analyzing their
patterns of keratin expression in culture and in transplants. Keratinocytes of all oral regions
synthesized high levels of keratins K5/K14 and K6/K16, K17, as expressed by cells of all
stratified squamous epithelia in culture. However, cells from different regions varied in their
expression in culture of retinoid-inducible (K19 and K13) and simple epithelial (K7, K8 and
K18) keratins. By these criteria, all oral cells could be classified as belonging to one of three …