Anti-HIV effect of beta subunit of human chorionic gonadotropin (βhCG) in vitro
AS Bourinbaiar, S Lee-Huang - Immunology letters, 1995 - Elsevier
Human chorionic gonadotropin (hCG)—a pregnancy-associated immunomodulating
hormone—has been recently shown in vitro to suppress reverse transcriptase activity in
chronically HIV-infected lymphocytes and monocytes and to block viral transmission
resulting from cell-cell contact between virus-carrying lymphocytes and placental
trophoblasts. In further pursuit of the query into the mechanism of action, purified α and β
subunits of hCG were tested for the inhibition of p24 gag protein synthesis in virus-producing …
hormone—has been recently shown in vitro to suppress reverse transcriptase activity in
chronically HIV-infected lymphocytes and monocytes and to block viral transmission
resulting from cell-cell contact between virus-carrying lymphocytes and placental
trophoblasts. In further pursuit of the query into the mechanism of action, purified α and β
subunits of hCG were tested for the inhibition of p24 gag protein synthesis in virus-producing …
