X-linked immune dysregulation, neonatal insulin dependent diabetes, and intractable diarrhoea.
JE Peake, RB McCrossin, G Byrne… - Archives of Disease in …, 1996 - fn.bmj.com
JE Peake, RB McCrossin, G Byrne, R Shepherd
Archives of Disease in Childhood-Fetal and Neonatal Edition, 1996•fn.bmj.comFour related male infants presented with neonatal diabetes mellitus, immune dysregulation
with extremely high concentrations of immunoglobulin E, and intractable diarrhoea. They
were all from one family, and all of them died. As far as is known this X-linked recessive
disorder has not been described before. It is suggested that this is a new immunodeficiency
in which type 2 T helper responses predominate.
with extremely high concentrations of immunoglobulin E, and intractable diarrhoea. They
were all from one family, and all of them died. As far as is known this X-linked recessive
disorder has not been described before. It is suggested that this is a new immunodeficiency
in which type 2 T helper responses predominate.
Four related male infants presented with neonatal diabetes mellitus, immune dysregulation with extremely high concentrations of immunoglobulin E, and intractable diarrhoea. They were all from one family, and all of them died. As far as is known this X-linked recessive disorder has not been described before. It is suggested that this is a new immunodeficiency in which type 2 T helper responses predominate.
fn.bmj.com