Streptococcus pyogenesinfection in mice
LK Husmann, DL Dillehay, VM Jennings, JR Scott - Microbial pathogenesis, 1996 - Elsevier
We inoculated 5 to 7-week-old female C3HeB/FeJ mice withStreptococcus pyogenesstrain
B514-Sm (type M50) by both an intranasal and intratracheal route and characterized the
resulting illness. Following intranasal inoculation, the animals developed signs of illness
within 1 to 8 days post-inoculation which correlated with acute, suppurative,
bronchopneumonia during histopathologic analysis; however, the relationship of response
to dose was non-linear, as seen previously in a small group of mice. 1Intratracheal …
B514-Sm (type M50) by both an intranasal and intratracheal route and characterized the
resulting illness. Following intranasal inoculation, the animals developed signs of illness
within 1 to 8 days post-inoculation which correlated with acute, suppurative,
bronchopneumonia during histopathologic analysis; however, the relationship of response
to dose was non-linear, as seen previously in a small group of mice. 1Intratracheal …