Leukocyte counts in children with sickle cell disease: comparative values in the steady state, vaso-occlusive crisis, and bacterial infection
GR Buchanan, BE Glader - American Journal of Diseases of …, 1978 - jamanetwork.com
• Total and differential WBC counts were measured in 88 children with siokle cell
hemoglobinopathies during the steady state, vaso-occlusive crisis, and bacterial infection.
Steady state leukocyte values were lower than anticipated on the basis of currently available
information. Total and segmented leukocyte numbers were greatly increased during vaso-
occlusive crisis and infection, but only with bacterial infection was there a consistent
increase in bands or nonsegmented leukocytes (mean, 4,580/μl). On the basis of these data …
hemoglobinopathies during the steady state, vaso-occlusive crisis, and bacterial infection.
Steady state leukocyte values were lower than anticipated on the basis of currently available
information. Total and segmented leukocyte numbers were greatly increased during vaso-
occlusive crisis and infection, but only with bacterial infection was there a consistent
increase in bands or nonsegmented leukocytes (mean, 4,580/μl). On the basis of these data …
