Diffuse panbronchiolitis: diagnosis and distinction from various pulmonary diseases with centrilobular interstitial foam cell accumulations

M Iwata, TV Colby, M Kitaichi - Human pathology, 1994 - Elsevier
Diffuse panbronchiolitis (DPB) is a clinicopathologic entity characterized histologically by
chronic inflammation principally affecting the respiratory bronchioles. Few pathologists
outside Japan are familiar with this entity. The most distinctive pathologic feature of DPB is
chronic inflammation and an accumulation of foam cells in the walls of the respiratory
bronchioles, adjacent alveolar ducts, and alveoli (PB unit lesion). The differential diagnosis
is important both clinically and histologically because of the similarity of DPB to other chronic …