Suppression of experimental autoimmune myasthenia gravis by nasal administration of acetylcholine receptor
CG Ma, GX Zhang, BG Xiao, J Link, T Olsson… - Journal of …, 1995 - Elsevier
Experimental autoimmune myasthenia gravis (EAMG) is a well established animal model,
which can be induced in various animal species and strains with acetylcholine receptor
(AChR) and represents an experimental counterpart of human myasthenia gravis (MG).
Current immunotherapies of both EAMG and MG are non-specific and limited by their
toxicity. Tolerance to EAMG has been achieved by oral administration of milligram quantities
of Torpedo AChR. In the present report we demonstrate that nasal administration of …
which can be induced in various animal species and strains with acetylcholine receptor
(AChR) and represents an experimental counterpart of human myasthenia gravis (MG).
Current immunotherapies of both EAMG and MG are non-specific and limited by their
toxicity. Tolerance to EAMG has been achieved by oral administration of milligram quantities
of Torpedo AChR. In the present report we demonstrate that nasal administration of …
