The elongin B ubiquitin homology domain: identification of Elongin B sequences important for interaction with Elongin C
CS Brower, A Shilatifard, T Mather, T Kamura… - Journal of Biological …, 1999 - ASBMB
Mammalian Elongin B is a 118-amino acid protein composed of an 84-amino acid amino-
terminal ubiquitin-like domain and a 34-amino acid carboxyl-terminal tail. Elongin B is found
in cells as a subunit of the heterodimeric Elongin BC complex, which was originally
identified as a positive regulator of RNA polymerase II elongation factor Elongin A and
subsequently as a component of the multiprotein von Hippel-Lindau tumor suppressor and
suppressor of cytokine signaling complexes. As part of our effort to understand how the …
terminal ubiquitin-like domain and a 34-amino acid carboxyl-terminal tail. Elongin B is found
in cells as a subunit of the heterodimeric Elongin BC complex, which was originally
identified as a positive regulator of RNA polymerase II elongation factor Elongin A and
subsequently as a component of the multiprotein von Hippel-Lindau tumor suppressor and
suppressor of cytokine signaling complexes. As part of our effort to understand how the …
