Effect of obesity on the relationship between very low density lipoprotein production rate and plasma triglyceride concentration in normal and hypertriglyceridemic …
GM Reaven, RM Bernstein - Metabolism, 1978 - Elsevier
GM Reaven, RM Bernstein
Metabolism, 1978•ElsevierThe effect of obesity on the relationship between very low density lipoprotein (VLDL)-
triglyceride (TG) production rate and concentration was studied in 80 subjects whose TG
concentrations ranged from 41–1315 mg 100 ml and whose relative weight varied from 0.74–
1.46. There was a positive correlation between VLDL-TG production rate and plasma TG
concentration in all 80 patients (r= 0.78), which was highly statistically significant (p< 0.001).
Both male and female subjects were subdivided into quartiles on the basis of relative weight; …
triglyceride (TG) production rate and concentration was studied in 80 subjects whose TG
concentrations ranged from 41–1315 mg 100 ml and whose relative weight varied from 0.74–
1.46. There was a positive correlation between VLDL-TG production rate and plasma TG
concentration in all 80 patients (r= 0.78), which was highly statistically significant (p< 0.001).
Both male and female subjects were subdivided into quartiles on the basis of relative weight; …
The effect of obesity on the relationship between very low density lipoprotein (VLDL)-triglyceride (TG) production rate and concentration was studied in 80 subjects whose TG concentrations ranged from 41–1315 mg 100 ml and whose relative weight varied from 0.74–1.46. There was a positive correlation between VLDL-TG production rate and plasma TG concentration in all 80 patients (r= 0.78), which was highly statistically significant (p< 0.001). Both male and female subjects were subdivided into quartiles on the basis of relative weight; the relationship between VLDL-TG production rate and plasma TG concentration was found to be comparable in all subgroups. These observations suggest that moderate degrees of obesity do not affect VLDL-TG kinetics in patients whose plasma TG levels vary over an extremely wide range.
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