Theiler's virus antigen detected in mouse spinal cord 2½ years after infection
HL Lipton, J Kratochvil, P Sethi, MC Dal Canto - Neurology, 1984 - AAN Enterprises
HL Lipton, J Kratochvil, P Sethi, MC Dal Canto
Neurology, 1984•AAN EnterprisesSpinal cord sections from mice injected with Theiler's murine encephalomyelitis virus
(TMEV) and surviving for 1 year and longer after infection were stained for virus antigen by
two immunohistochemical techniques. Virus antigen was detected from 1 to 2½ years after
infection, a time when no virus was recovered at an assay sensitivity of 50 plaqueforming
units per gram of tissue. The implication this has regarding the detection of a virus in MS is
discussed.
(TMEV) and surviving for 1 year and longer after infection were stained for virus antigen by
two immunohistochemical techniques. Virus antigen was detected from 1 to 2½ years after
infection, a time when no virus was recovered at an assay sensitivity of 50 plaqueforming
units per gram of tissue. The implication this has regarding the detection of a virus in MS is
discussed.
Spinal cord sections from mice injected with Theiler's murine encephalomyelitis virus (TMEV) and surviving for 1 year and longer after infection were stained for virus antigen by two immunohistochemical techniques. Virus antigen was detected from 1 to 2½ years after infection, a time when no virus was recovered at an assay sensitivity of 50 plaqueforming units per gram of tissue. The implication this has regarding the detection of a virus in MS is discussed.
American Academy of Neurology