Molecular species of hepadnavirus core and envelope polypeptides in hepatocyte plasma membrane of woodchucks with acute and chronic viral hepatitis
TI Michalak, B Lin - Hepatology, 1994 - journals.lww.com
Hepadnaviral antigens exposed on hepatocytes serve as targets and as possible
modulators of immunopathogenic reactions causing liver damage. To identify molecular
species of viral proteins at the liver cell surface and the relationship between their
expression and the persistence and severity of virus–induced liver injury, we examined
woodchuck hepatitis virus core and envelope polypeptides in host hepatocyte plasma
membranes from acute and chronic hepatitis. Western blot analysis revealed that two virus …
modulators of immunopathogenic reactions causing liver damage. To identify molecular
species of viral proteins at the liver cell surface and the relationship between their
expression and the persistence and severity of virus–induced liver injury, we examined
woodchuck hepatitis virus core and envelope polypeptides in host hepatocyte plasma
membranes from acute and chronic hepatitis. Western blot analysis revealed that two virus …