PGH2, TxA2 and PGI2 have potent and differentiated actions on human uterine contractility
L Wilhelmsson, M Wikland, N Wiqvist - Prostaglandins, 1981 - Elsevier
The contractile response to three different prostanoids of the isolated human myometrium
and the different layers of the utero-tubal junction (UTJ) was studied in vitro. The
prostaglandin endoperoxide, PGH 2, stimulated contractility of both the myometrium and the
outer and inner muscle layers of the UTJ, whereas the intermediate layer of the UTJ was
inhibited. Thromboxane A 2 generated from PGH 2 and a thromboxane synthase
preparation caused a stimulation of both the myometrium and all three layers of the UTJ. The …
and the different layers of the utero-tubal junction (UTJ) was studied in vitro. The
prostaglandin endoperoxide, PGH 2, stimulated contractility of both the myometrium and the
outer and inner muscle layers of the UTJ, whereas the intermediate layer of the UTJ was
inhibited. Thromboxane A 2 generated from PGH 2 and a thromboxane synthase
preparation caused a stimulation of both the myometrium and all three layers of the UTJ. The …