New Granulocyte Antigens Demonstrated by Microgranulocytotoxicity Assay

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Abstract

Although granulocyte transfusions and bone marrow transplantation are becoming common clinical modalities, our knowledge of surface nonerythroid, nonlymphoid, non-HLA hematopoetic antigens remains very incomplete. Accordingly, we have systematically screened sera from recipients of multiple granulocyte and whole blood transfusions, and immunoneutropenic patients for antibodies directed primarily at granulocytes.

Authors

J. S. Thompson, V. L. Overlin, J. M. Herbick, C. D. Severson, F. H. J. Claas, J. D. 'Amaro, C. P. Burns, R. G. Strauss, J. A. Koepke