Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Pancreatic Cancer (Jul 2025)
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

Effect of Heparin and Heparin Fractions on Platelet Aggregation
Edwin W. Salzman, … , Jack N. Lindon, Leonard Favreau
Edwin W. Salzman, … , Jack N. Lindon, Leonard Favreau
Published January 1, 1980
Citation Information: J Clin Invest. 1980;65(1):64-73. https://doi.org/10.1172/JCI109661.
View: Text | PDF
Research Article Article has an altmetric score of 12

Effect of Heparin and Heparin Fractions on Platelet Aggregation

  • Text
  • PDF
Abstract

Porcine intestinal mucosal heparin induced aggregation of platelets in citrated platelet-rich plasma and enhanced platelet aggregation and serotonin secretion induced by other agents. This action of heparin was blocked by substances that elevate platelet cyclic AMP and by EDTA but not by inhibitors of platelet cyclooxygenase. The effect was not inhibited by apyrase or by N-amylthio-5′-AMP and therefore did not require the action of ADP, nor was there activation of platelet phospholipase. Platelet aggregation by heparin required a plasma cofactor different from the cofactor required for ristocetin.

Authors

Edwin W. Salzman, Robert D. Rosenberg, Marianne H. Smith, Jack N. Lindon, Leonard Favreau

×

Total citations by year

Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 1980 1979 1974 1973 1949 Total
Citations: 1 4 1 1 2 1 5 3 3 3 2 5 9 10 4 8 5 7 9 4 5 10 9 8 17 14 17 14 15 14 18 11 11 22 19 18 19 17 30 18 21 12 18 13 8 1 1 1 1 469
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (469)

Title and authors Publication Year
Multifunctional Slippery Nanoemulsion-Infused Porous Nitric Oxide-Releasing Surfaces
Nguyen GH, Garren M, Wu Y, Mondal A, Handa H, Brisbois EJ
Journal of colloid and interface science 2025
Comparison of Blood Concentration and Weight-Based Heparin and Protamine Dosing Strategies for Cardiopulmonary Bypass: A Systematic Review and Meta-Analysis.
Raner G, Hu Y, Trowbridge C, Zhang L, Logan J, Wu X, Zhang X
Cureus 2024
Current and Future Roles of Glycoprotein IIb–IIIa Inhibitors in Primary Angioplasty for ST-Segment Elevation Myocardial Infarction
De Luca G, Verburg A, Hof AV, ten Berg J, Kereiakes DJ, Coller BS, Gibson CM
Biomedicines 2024
Management of Therapeutic-intensity Unfractionated Heparin: A Narrative Review on Critical Points
Gouin-Thibault I, Mansour A, Hardy M, Guéret P, de Maistre E, Siguret V, Cuker A, Mullier F, Lecompte T
TH Open: Companion Journal to Thrombosis and Haemostasis 2024
Imaging flow cytometry as a novel approach for the diagnosis of heparin‐induced thrombocytopenia
Carré J, Demont Y, Mouton C, Vayne C, Guéry E, Voyer A, Garçon L, Le Guyader M, Demagny J
British Journal of Haematology 2024
Critical Analysis of Thrombocytopenia Associated With Glycoprotein IIb/IIIa Inhibitors and Potential Role of Zalunfiban, a Novel Small Molecule Glycoprotein Inhibitor, in Understanding the Mechanism(s).
Rikken SAOF, van 't Hof AWJ, Ten Berg JM, Kereiakes DJ, Coller BS
Journal of the American Heart Association 2023
Effects of ex vivo blood anticoagulation and preanalytical processing time on the proteome content of platelets
Yunga ST, Gower AJ, Melrose AR, Fitzgerald MK, Rajendran A, Lusardi TA, Armstrong RJ, Minnier J, Jordan KR, McCarty OJ, David LL, Wilmarth PA, Reddy AP, Aslan JE
Journal of Thrombosis and Haemostasis 2022
Low Molecular Weight Heparins (LMWH) and Implications along Pregnancy: a Focus on the Placenta
S Zullino, S Clemenza, F Mecacci, F Petraglia
Reproductive sciences (Thousand Oaks, Calif.) 2021
Heparin and Derivatives for Advanced Cell Therapies
S Laner-Plamberger, M Oeller, E Rohde, K Schallmoser, D Strunk
International journal of molecular sciences 2021
Electroconductive Graphene-Containing Polymeric Patch: A Promising Platform for Future Cardiac Repair
A Talebi, S Labbaf, F Karimzadeh, E Masaeli, MH Esfahani
ACS Biomaterials Science & Engineering 2020
Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
T Vögtle, S Sharma, J Mori, Z Nagy, D Semeniak, C Scandola, MJ Geer, CW Smith, J Lane, S Pollack, R Lassila, A Jouppila, AJ Barr, DJ Ogg, TD Howard, HJ McMiken, J Warwicker, C Geh, R Rowlinson, WM Abbott, A Eckly, H Schulze, GJ Wright, A Mazharian, K Fütterer, S Rajesh, MR Douglas, YA Senis
eLife 2019
Shear-induced platelet aggregation: 3D-grayscale microfluidics for repeatable and localized occlusive thrombosis
MT Griffin, D Kim, DN Ku
Biomicrofluidics 2019
Assessing the Thrombogenic Potential of Heart Valve Prostheses: An Approach for a Standardized In-Vitro Method
T Linde, J Clauser, B Meuris, U Steinseifer
Cardiovascular Engineering and Technology 2019
From unfractionated heparin to pentasaccharide: Paradigm of rigorous science growing in the understanding of the in vivo thrombin generation
G Spadarella, AD Minno, MB Donati, M Mormile, I Ventre, GD Minno
Blood Reviews 2019
Antithrombotic, antimicrobial activities, and biocompatibility of surface-functionalized titanium
G Zhang, X Zhang, Z Sun, X Yao, X Zhang
Journal of Materials Research 2019
VV extracorporeal life support for the Third Millennium: will we need anticoagulation?
D Eytan, Y Bitterman, GM Annich
Journal of Thoracic Disease 2018
Blood loss of total knee arthroplasty in osteoarthritis: an analysis of influential factors
Y Hu, Q Li, BG Wei, XS Zhang, TT Torsha, J Xiao, ZJ Shi
Journal of orthopaedic surgery and research 2018
Novel Surfaces in Extracorporeal Membrane Oxygenation Circuits
A Ontaneda, GM Annich
Frontiers in Medicine 2018
Platelets in Thrombotic and Non-Thrombotic Disorders
P Gresele, NS Kleiman, JA Lopez, CP Page
Platelets in Thrombotic and Non-Thrombotic Disorders 2017
Biomimetic Heparan Sulfate-Like Coated ePTFE Grafts Reduce In-graft Neointimal Hyperplasia in Ovine Carotids
B Wulff, S Stahlhoff, R Vonthein, A Schmidt, M Sigler, GB Torsello, M Herten
Annals of Vascular Surgery 2017
Hemodynamic studies of platelet thrombosis using microfluidics
SM Hastings, MT Griffin, DN Ku
Platelets 2017
Advances in Experimental Medicine and Biology
FS Sharif-Askari, SA Sulaiman, NS Sharif-Askari
Advances in experimental medicine and biology 2016
Microfluidics for simultaneous quantification of platelet adhesion and blood viscosity
E Yeom, JH Park, YJ Kang, SJ Lee
Scientific Reports 2016
Vitrectomy for Proliferative Diabetic Retinopathy in a Patient with Heparin-Induced Thrombocytopenia
T Fujii, M Akashi, S Morishita, M Fukumoto, H Suzuki, T Kobayashi, T Kida, M Kagitani, I Morino, T Ikeda
Case Reports in Ophthalmology 2016
Anticoagulant mechanism and platelet deaggregation property of a non-cytotoxic, acidic phospholipase A2 purified from Indian cobra (Naja naja) venom: Inhibition of anticoagulant activity by low molecular weight heparin
S Dutta, D Gogoi, AK Mukherjee
Biochimie 2015
Aspirin and heparin in pregnancy
E Grandone, M Villani, GL Tiscia
Expert Opinion on Pharmacotherapy 2015
Zastosowanie koncentratu czynników zespołu protrombiny w leczeniu zaburzeń hemostazy osoczowej po operacji transplantacji serca
T Urbanowicz, M Puślecki, W Budniak, P Buczkowski, J Tomczyk, M Walczak, M Ligowski, I Katyńska, M Jemielity
Acta Haematologica Polonica 2013
Ex Vivo Lung Evaluation of Prearrest Heparinization in Donation After Cardiac Death:
PG Sanchez, GJ Bittle, K Williams, C Pasrija, K Xu, X Wei, ZJ Wu, BP Griffith
Annals of Surgery 2013
Retina
G Staurenghi, F Bottoni, A Giani
Retina 2013
Anesthetic Pharmacology and Physiology
D Royston
Anesthetic Pharmacology and Physiology 2013
The antineoplastic effect of low-molecular-weight heparins - a literature review
J Bochenek, M Püsküllüoğlu, K Krzemieniecki
WSPOLCZESNA ONKOL 2013
Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Profile of the Oral Antiplatelet Agent Ticagrelor :
R Teng
Clinical Pharmacokinetics 2012
Dacie and Lewis Practical Haematology
F Regan
Dacie and Lewis Practical Haematology 2012
Advances in Carbohydrate Chemistry and Biochemistry
D Mirelman, EA Bayer, Y Reisner
Advances in Carbohydrate Chemistry and Biochemistry 2012
Lack of clinically significant pharmacological interactions between ticagrelor and enoxaparin or unfractionated heparin in healthy subjects: Ticagrelor and enoxaparin/UFH
R Teng, K Butler
Journal of Clinical Pharmacy and Therapeutics 2012
Pharmacologic Management of Coagulopathy in Cardiac Surgery: An Update
T Rozental, L Shore-Lesserson
Journal of Cardiothoracic and Vascular Anesthesia 2012
Methodological considerations for the assessment of ADP induced platelet aggregation using the Multiplate® analyser
LR Johnston, PD Larsen, AC la Flamme, SA Harding
Platelets 2012
Parenteral Anticoagulants
DA Garcia, TP Baglin, JI Weitz, MM Samama
Chest 2012
Six years of clinical follow-up with endothelial cell–seeded small-diameter vascular grafts during coronary bypass surgery
PM Dohmen, A Pruss, C Koch, AC Borges, W Konertz
Journal of Tissue Engineering 2012
Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Profile of the Oral Antiplatelet Agent Ticagrelor:
R Teng
Clinical Pharmacokinetics 2012
Heparin promotes platelet responsiveness by potentiating αIIbβ3-mediated outside-in signaling
C Gao, B Boylan, J Fang, DA Wilcox, DK Newman, PJ Newman
Blood 2011
Gynecologic Oncology
A Vasilev, S Vasilev
Gynecologic Oncology 2011
Immobilization of an antithrombin–heparin complex on gold: Anticoagulant properties and platelet interactions
KN Sask, WG McClung, LR Berry, AK Chan, JL Brash
Acta Biomaterialia 2011
Interventional Cardiology
G Sangiorgi, A Mauriello, S Trimarchi, E Bonanno, LG Spagnoli
Interventional Cardiology 2011
The artificial endothelium
MM Reynolds, GM Annich
Organogenesis 2011
Heparin modulates the conformation and signaling of platelet integrin αIIbβ3
M Yagi, J Murray, K Strand, S Blystone, G Interlandi, Y Suda, M Sobel
Thrombosis Research 2011
Low molecular weight heparin inhibits melanoma cell adhesion and migration through a PKCa/JNK signaling pathway inducing actin cytoskeleton changes
G Chalkiadaki, D Nikitovic, P Katonis, A Berdiaki, A Tsatsakis, I Kotsikogianni, NK Karamanos, GN Tzanakakis
Cancer Letters 2011
Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee
Annual Reports in Medicinal Chemistry Volume 46 2011
Henry's Clinical Diagnosis and Management by Laboratory Methods
JL Miller, AK Rao
Henry's Clinical Diagnosis and Management by Laboratory Methods 2011
Thoraco-Abdominal Aorta
R Chiesa, G Melissano, A Zangrillo
2011
Preoperative Heparin Therapy Causes Immune-Mediated Hypotension Upon Heparin Administration for Cardiac Surgery
PA Casthely, V Defilippi, L Cornwell, Z Samuel, T Yoganathan, C Komer, S Cisbarros, A Acevedo
Journal of Cardiothoracic and Vascular Anesthesia 2010
Heparin versus prostacyclin in continuous hemodiafiltration for acute renal failure: Effects on platelet function in the systemic circulation and across the filter
A Arcangeli, B Rocca, G Salvatori, M Ciancia, RD Cristofaro, M Antonelli
Thrombosis Research 2010
Improved biocompatibility of thrombo-resistant iron-polysaccharides multilayer coatings on Nitinols
Y Ma, M Liu, X Yue, Z Zha, Z Dai
International Journal of Biological Macromolecules 2010
Acute Pulmonary Embolism
PD Stein, F Matta
Current Problems in Cardiology 2010
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Hyperserotonemia in autism: activity of 5HT-associated platelet proteins
D Hranilović, Z Bujas-Petković, M Tomičić, T Bordukalo-Nikšić, S Blažević, L Čičin-Šain
Journal of Neural Transmission 2009
Self-assembled hemocompatible coating on poly (vinyl chloride) surface
Z Zha, Y Ma, X Yue, M Liu, Z Dai
Applied Surface Science 2009
Isolation and Characterization of Low Molecular Weight Glycosaminoglycans from Marine Mollusc Amussium pleuronectus (Linne) using Chromatography
R Saravanan, A Shanmugam
Applied Biochemistry and Biotechnology 2009
Pre-analytical effects of pneumatic tube transport on impedance platelet aggregometry
D Bolliger, MD Seeberger, KA Tanaka, S Dell-Kuster, M Gregor, U Zenklusen, M Grapow, DA Tsakiris, M Filipovic
Platelets 2009
The prevention and treatment of venous thromboembolism with LMWHs and new anticoagulants
AD Blann, CW Khoo
Vascular Health and Risk Management 2009
Heparin-Induced Thrombocytopenia
E Shantsila, GY Lip, BH Chong
Chest 2009
Hypothermic cardiopulmonary bypass as a determinant of late thrombocytopenia following cardiac operations in pediatric patients
M Ranucci, C Carlucci, G Isgrò, S Brozzi, A Boncilli, E Costa, A Frigiola
Acta Anaesthesiologica Scandinavica 2009
Fundamental and Clinical Cardiology Series
PD Stein
Cardiovascular Disease in the Elderly 2008
Impact of bivalirudin or unfractionated heparin on platelet aggregation in patients pretreated with 600 mg clopidogrel undergoing elective percutaneous coronary intervention
D Sibbing, G Busch, S Braun, S Jawansky, A Schomig, A Kastrati, I Ott, N Beckerath
European Heart Journal 2008
Dacie y Lewis. Hematología Práctica
BJ Bain, N Win
Dacie y Lewis. Hematología Práctica 2008
Immobilization of heparin: approaches and applications
S Murugesan, J Xie, RJ Linhardt
Current topics in medicinal chemistry 2008
Parenteral Anticoagulants
J Hirsh, KA Bauer, MB Donati, M Gould, MM Samama, JI Weitz
Chest 2008
Low-molecular-weight heparin use in acute coronary syndromes and percutaneous coronary interventions: An update
JJ Link, JJ Warner, JA Lemos
Current Cardiovascular Risk Reports 2007
An in vitro Method for Assessing Biomaterial-Associated Platelet Activation
NG LaFayette, AM Skrzypchak, S Merz, RH Bartlett, GM Annich
ASAIO Journal 2007
Prevention of perioperative thromboembolism in patients with atrial fibrillation
G Beldi, L Beng, G Siegel, S Bisch-Knaden, D Candinas
British Journal of Surgery 2007
Regulation of Thrombin Activity—Pharmacologic and Structural Aspects
KA Tanaka, JH Levy
Hematology/Oncology Clinics of North America 2007
Comparison of Platelet Function and Morphology in Patients Undergoing Percutaneous Coronary Intervention Receiving Bivalirudin Versus Unfractionated Heparin Versus Clopidogrel Pretreatment and Bivalirudin
SX Anand, MC Kim, M Kamran, SK Sharma, AS Kini, J Fareed, DA Hoppensteadt, F Carbon, E Cavusoglu, D Varon, JF Viles-Gonzalez, JJ Badimon, JD Marmur
The American Journal of Cardiology 2007
An in vitro Method for Assessing Biomaterial-Associated Platelet Activation:
NG LaFayette, AM Skrzypchak, S Merz, RH Bartlett, GM Annich
ASAIO Journal 2007
Effect of varying nitric oxide release to prevent platelet consumption and preserve platelet function in an in vivo model of extracorporeal circulation
AM Skrzypchak, NG Lafayette, RH Bartlett, Z Zhou, MC Frost, ME Meyerhoff, MM Reynolds, GM Annich
Perfusion 2007
Promotion of proinflammatory interactions between platelets and monocytes by unfractionated heparin
SA Harding, JN Din, J Sarma, DH Josephs, KA Fox, DE Newby
Heart (British Cardiac Society) 2006
Guidelines on the use and monitoring of heparin
T Baglin, TW Barrowcliffe, A Cohen, M Greaves
British Journal of Haematology 2006
Effect of recombinant activated protein C and low-dose heparin on neutrophil-endothelial cell interactions in septic shock*
LA Kirschenbaum, WC Lopez, P Ohrum, A Tsen, J Khazin, ME Astiz
Critical Care Medicine 2006
Aspirin reduces platelet aggregation during high-energy excimer laser
R Huang, RB Patel, H Ma, K Taylor, GS Abela
Lasers in Surgery and Medicine 2006
Diagnosis and treatment of heparin-induced thrombocytopenia in neonates and children
L Risch, AR Huber, M Schmugge
Thrombosis Research 2006
Collection and handling of blood
SM Lewis, N Tatsumi
Dacie and Lewis Practical Haematology 2006
Effect of recombinant activated protein C and low-dose heparin on neutrophil-endothelial cell interactions in septic shock*:
LA Kirschenbaum, WC Lopez, P Ohrum, A Tsen, J Khazin, ME Astiz
Critical Care Medicine 2006
Present and Future Anticoagulants
ME Stone, L Shore-Lesserson
Advances in Anesthesia 2006
Unfractionated Heparin Reduces the Anti-Platelet Effects of Abciximab but not Eptifibatide During PCI
EN Deliargyris, B Upadhya, LG Melton, C Thompson, M Fisher, DA Gabriel, GJ Dehmer, DC Sane
Clinical and Applied Thrombosis/Hemostasis 2006
Coagulation and fibrinolytic profiles and appropriate use of heparin after living-donor liver transplantation
J Kaneko, Y Sugawara, S Tamura, J Togashi, Y Matsui, N Akamatsu, Y Kishi, M Makuuchi
Clinical Transplantation 2005
Potentiation of platelet aggregation by heparin in human whole blood is attenuated by P2Y12 and P2Y1 antagonists but not aspirin
RF Storey, JA May, S Heptinstall
Thrombosis Research 2005
Chemistry and Biology of Heparin and Heparan Sulfate
JM Walenga, WP Jeske, J Fareed
Chemistry and Biology of Heparin and Heparan Sulfate 2005
Heparin Therapy Leads to Platelet Activation and Prolongation of PFA-100 Closure Time
MS Williams, LS Ngalla
Journal of cardiovascular pharmacology and therapeutics 2005
Analysis of cellular morphology, adhesion, and proliferation on uncoated and differently coated PVC tubes used in extracorporeal circulation (ECC)
PL Moreira, PR Marreco, AM Moraes, ML Wada, SC Genari
Journal of Biomedical Materials Research 2004
Acenocoumarol associated priapism: report of a case
S Touloupidis, I Zoumpos, C Kalaitzis, T Vogiatzaki, P Chloropoulou
Andrologia 2004
Intravenous abciximab for parent vessel thrombus during basilar apex aneurysm coil embolization: Case report and literature review
BR Bendok, DJ Padalino, EI Levy, AI Qureshi, LR Guterman, LN Hopkins
Surgical neurology 2004
Anticoagulation in Hospitalized Patients With Renal Insufficiency
N Thorevska, Y Amoateng-Adjepong, R Sabahi, I Schiopescu, A Salloum, V Muralidharan, CA Manthous
Chest 2004
Thrombotic Complications in Three Hemodialysis Patients With Heparin-Induced Thrombocytopenia Type I
S Suzuki, S Sakamoto, M Matsuo, C Shimano, T Kuroda, T Matsuo
Clinical and Applied Thrombosis/Hemostasis 2004
Characteristics of the hemostatic action of KFA-1411, an inhibitor of coagulation factor Xa (FXa), in humans and various animals
K HARA, T HONMA, A MATSUZAWA, A MATSUZAWA, M UCHIDA, T KOIZUMI, S AKAHANE, M KOJIMA
The Journal of Toxicological Sciences 2003
Heparin Monitoring in Sheep by Activated Partial Thromboplastin Time
SG Park, SC Kim, MJ Choi, HS Lee, BG Min, J Cheong, K Lee
Artificial Organs 2003
Platelet responses and coagulation activation on polylactide and heparin-polycaprolactone-L-lactide -coated polylactide stent struts
EM Hietala, P Maasilta, T Välimaa, AL Harjula, P Törmälä, US Salminen, R Lassila
Journal of Biomedical Materials Research 2003
Pharmacologic platelet anesthesia by glycoprotein IIb/IIIa complex antagonist and argatroban during in vitro extracorporeal circulation
S Kanemitsu, M Nishikawa, K Onoda, T Shimono, H Shimpo, A Yazaki, K Tanaka, H Shiku, I Yada
The Journal of Thoracic and Cardiovascular Surgery 2003
Effects of argatroban and heparin on thrombus formation and tissue plasminogen activator-induced thrombolysis in a microvascular thrombosis model
K Yamada, H Tsuji, S Kimura, H Kato, S Yano, N Ukimura, Y Yamada, K Nakagawa, M Nakagawa
Thrombosis Research 2003
Heparin Modulates Integrin-Mediated Cellular Adhesion: Specificity of Interactions with α and β Integrin Subunits
MS da Silva, JA Horton, JM Wijelath, LW Blystone, WR Fish, E Wijelath, K Strand, SD Blystone, M Sobel
Cell communication & adhesion 2003
Simultaneous Testing of the Heparin Effect on the Soluble Phase and Platelet Component of Hemostasis
LG Melton, DA Gabriel, GJ Dehmer
The American Journal of the Medical Sciences 2003
Platelet Loss across the Hemofilter during Continuous Hemofiltration
J Mulder, HK Tan, R Bellomo, W Silvester
The International Journal of Artificial Organs 2003
Anticoagulation Therapy in Children:
MD Ronghe, C Halsey, NJ Goulden
Pediatric Drugs 2003
The Hemostatic Defect of Cardiopulmonary Bypass
MD Linden
Journal of Thrombosis and Thrombolysis 2003
Hypothermia with Heparin-Coated Circuits and Low Dose Systemic Heparinization in Neurosurgery
Y Hachiro, K Morishita, R Koshima, S Nakashima, N Takagi, M Tsukamoto, T Abe, K Hashi
Artificial Organs 2002
Effects of abciximab on the acute pathology of blood vessels after arterial stenting in nonhuman primates
T Palmerini, MA Nedelman, LE Scudder, MT Nakada, RE Jordan, S Smyth, RE Gordon, JT Fallon, BS Coller
Journal of the American College of Cardiology 2002
The Low Molecular Weight Heparin, Tinzaparin, in Thrombosis and Beyond
SA Mousa
Cardiovascular Drug Reviews 2002
A whole blood flow cytometric determination of platelet activation by unfractionated and low molecular weight heparin in vitro
B Klein, A Faridi, GF Tempelhoff, L Heilmann, C Mittermayer, W Rath
Thrombosis Research 2002
Pharmacodynamic profile of short-term readministration of abciximab in healthy subjects
J Freedman, MA Mascelli, JC Pezzullo, ES Barnathan, B Frederick, RE Jordan, DR Abernethy
American Heart Journal 2002
Randomized double-blind safety study of enoxaparin versus unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes treated with tirofiban and aspirin: The ACUTE II study
M Cohen, P Théroux, S Borzak, MJ Frey, HD White, WV Mieghem, F Senatore, J Lis, R Mukherjee, K Harris, F Bigonzi
American Heart Journal 2002
Thrombin generation and its inhibition: a review of the scientific basis and mechanism of action of anticoagulant therapies
CP Walker, D Royston
British Journal of Anaesthesia 2002
Intraarterially administered abciximab as an adjuvant thrombolytic therapy: report of three cases
O-Ki Kwon, Ki Jae Lee, Moon Hee Han, Chang-Wan Oh, Dae Hee Han, Young Cho Koh
American Journal of Neuroradiology 2002
Decreased platelet reactivity in blood anticoagulated with bivalirudin or enoxaparin compared with unfractionated heparin: implications for coronary intervention
Atul Aggarwal, Burton E Sobel, David J Schneider
Journal of Thrombosis and Thrombolysis 2002
DRUG-INDUCED AND DRUG-DEPENDENT IMMUNE THROMBOCYTOPENIAS
A Greinacher, P Eichler, N Lubenow, V Kiefel
Reviews in Clinical and Experimental Hematology 2001
Interaction of blood components with heparin-immobilized polyurethanes prepared by plasma glow discharge
IK Kang, EJ Seo, MW Huh, KH Kim
Journal of Biomaterials Science, Polymer Edition 2001
Heparin modulates integrin function in human platelets
M Sobel, WR Fish, N Toma, S Luo, K Bird, K Mori, S Kusumoto, SD Blystone, Y Suda
Journal of Vascular Surgery 2001
Tratamiento anticoagulante
ER Hernando, JH Santos, CP Santos, JA Fernández
Medicine - Programa de Formación Médica Continuada Acreditado 2001
Leukocyte-platelet aggregation, platelet surface P-selectin, and platelet surface glycoprotein IIIa after percutaneous coronary intervention: Effects of dalteparin or unfractionated heparin in combination with abciximab
MI Furman, DJ Kereiakes, LA Krueger, MN Mueller, K Pieper, TM Broderick, JF Schneider, WL Howard, ML Fox, MR Barnard, AL Frelinger, AD Michelson
American Heart Journal 2001
Platelet Adhesion to Heparin Coated Oxygenator Fibers Under In Vitro Static Conditions: Impact of Temperature:
Y Niimi, Y Ishiguro, Y Nakata, T Goto, S Morita, S Yamane
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2001
Hemostatic Abnormalities in Cardiopulmonary Bypass: Pathophysiologic and Transfusion Considerations
K Kottke-Marchant, S Sapatnekar
Seminars in cardiothoracic and vascular anesthesia 2001
Guide to Anticoagulant Therapy: Heparin: A Statement for Healthcare Professionals From the American Heart Association
J Hirsh, SS Anand, JL Halperin, V Fuster
Circulation 2001
Reduction of heparin dose is not beneficial to platelet function
T Nakajima, K Kawazoe, K Ishibashi, Y Kubota, T Sasaki, H Izumoto, T Nitatori
The Annals of Thoracic Surgery 2000
Albumin and heparin multilayer coatings for blood-contacting medical devices
E Brynda, M Houska, M Jirou?kov�, JE Dyr
Journal of Biomedical Materials Research 2000
Importance of Uniform Heparin Coating on Biopolymers
PL Moreira, ML Wada, WP Novello
Artificial Organs 2000
Effects of various anticoagulant treatments on von Willebrand factor release in unstable angina
G Montalescot, JP Collet, L Lison, R Choussat, A Ankri, E Vicaut, K Perlemuter, F Philippe, G Drobinski, D Thomas
Journal of the American College of Cardiology 2000
Assessment of low-molecular-weight heparin trials in cardiology
RI Shulman
Pharmacology & Therapeutics 2000
Surface characterization and in vitro blood compatibility of poly(ethylene terephthalate) immobilized with insulin and/or heparin using plasma glow discharge
YJ Kim, IK Kang, MW Huh, SC Yoon
Biomaterials 2000
Preparation and characterization of hydrophobic polymeric films that are thromboresistant via nitric oxide release
KA Mowery, MH Schoenfisch, JE Saavedra, LK Keefer, ME Meyerhoff
Biomaterials 2000
Platelets
JN George
The Lancet 2000
Therapeutic heparin concentrations augment platelet reactivity: Implications for the pharmacologic assessment of the glycoprotein IIb/IIIa antagonist abciximab
MA Mascelli, NS Kleiman, SJ Marciniak, L Damaraju, HF Weisman, RE Jordan
American Heart Journal 2000
Abciximab, ticlopidine, and concomitant abciximab-ticlopidine therapy: Ex vivo platelet aggregation inhibition profiles in patients undergoing percutaneous coronary interventions
NS Kleiman, N Grazeiadei, K Maresh, RJ Taylor, B Frederick, ET Lance, MB Effron, RE Jordan, MA Mascelli
American Heart Journal 2000
The emerging role of low-molecular-weight heparin in cardiovascular medicine
J Hirsh, SM Bates
Progress in Cardiovascular Diseases 2000
Pharmacokinetics and Pharmacodynamics of Sibrafiban, an Orally Administered GP IIb/IIIa Antagonist, following Coadministration of Aspirin and Heparin
JD Reimann, NB Modi, W Novotny
The Journal of Clinical Pharmacology 2000
Reduced platelet activation and thrombosis in extracorporeal circuits coated with nitric oxide release polymers:
GM Annich, JP Meinhardt, KA Mowery, BA Ashton, SI Merz, RB Hirschl, ME Meyerhoff, RH Bartlett
Critical Care Medicine 2000
Estudo experimental do uso de um antagonista do receptor da glicoproteína IIb/IIIa das placentas na prevenção de tromboses em microanastomoses vasculares
MI Oide
Acta Ortopédica Brasileira 2000
State-of-the-Art Review : Heparin-Induced Thrombocytopenia: A Critical Risk/Benefit Analysis of Patients in Intensive Care Treated With R-Hirudin
JF Schenk, G Berg, S Mörsdorf, B Stefan, H Kroll, B Krischek, G Pindur, H Schieffer, E Wenzel
Clinical and Applied Thrombosis/Hemostasis 2000
In Vivo Thrombin Generation and Activity During and After Intravenous Infusion of Heparin or Recombinant Hirudin in Patients With Unstable Angina Pectoris
PA Merlini, D Ardissino, RD Rosenberg, E Colombi, P Agricola, L Oltrona, F Ottani, M Galvani, KA Bauer, B Bottasso, F Bertocchi, PM Mannucci
Arteriosclerosis, thrombosis, and vascular biology 2000
Heparin-Induced Thrombocytopenia: Minimising the Risks in the Elderly Patient
B Tardy-Poncet, B Tardy
Drugs & Aging 2000
Combination therapy with tirofiban and enoxaparin in acute coronary syndromes
M Cohen, P Théroux, S Weber, P Laramée, T Huynh, S Borzak, JG Diodati, IB Squire, LI Deckelbaum, AR Thornton, KE Harris, FL Sax, MW Lo, HD White
International Journal of Cardiology 1999
Inhibition of platelet aggregation by the GPIIb/IIIa antagonist Reopro does not significantly prolong xenograft survival in an ex vivo model
AE Fiane, V Videm, TE Mollnes, K Høgåsen, T Hovig
Transplant International 1999
Blood compatibility of surfaces with immobilized albumin-heparin conjugate and effect of endothelial cell seeding on platelet adhesion
GW Bos, NM Scharenborg, AA Poot, GH Engbers, T Beugeling, WG van Aken, J Feijen
Journal of Biomedical Materials Research 1999
Bleeding complications with enoxaparin for deep venous thrombosis prophylaxis
MD Shaieb, BN Watson, RE Atkinson
The Journal of Arthroplasty 1999
Outpatient treatment of deep vein thrombosis: translating clinical trials into practice
AS Dunn, B Coller
The American Journal of Medicine 1999
Thrombin-induced platelet activation is inhibited by high- and low-molecular-weight heparin
ED Candia, RD Cristofaro, R Landolfi
Circulation 1999
Antithrombotic therapy of unstable angina and non-Q-wave myocardial infarction
M Ferrario, PA Merlini, S Lucreziotti, A Poli, F Cantù, G Gobbi, E Bramucci, A Mussini, D Ardissino
International Journal of Cardiology 1999
Comparison of low-molecular-weight heparin (enoxaparin sodium) and standard unfractionated heparin for haemodialysis anticoagulation
D Saltissi, C Morgan, J Westhuyzen, H Healy
Nephrology Dialysis Transplantation 1999
Heparin-Induced Thrombocytopenia: Historical Review
HL Messmore
Clinical and Applied Thrombosis/Hemostasis 1999
The Effects of Heparin Coating of Oxygenator Fibers on Platelet Adhesion and Protein Adsorption:
Y Niimi, F Ichinose, Y Ishiguro, K Terui, S Uezono, S Morita, S Yamane
Anesthesia & Analgesia 1999
A single dose of dalteparin effectively prevents clotting during haemodialysis
S Sagedal, A Hartmann, K Sundstrøm, S Bjørnsen, P Fauchald, F Brosstad
Nephrology Dialysis Transplantation 1999
Hämostaseologie
G Müller-Berghaus, B Pötzsch
Hämostaseologie 1999
Antithrombotics
AC Uprichard, KP Gallagher
1999
Die Venenthrombose
V Hach-Wunderle, W Theiss
1999
Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents
A Koenig, K Norgard-Sumnicht, R Linhardt, A Varki
Journal of Clinical Investigation 1998
Micro stent implantation in patients with acute myocardial infarction without anticoagulation: Clinical experience with two different antithrombotic protocols
PV Oemrawsingh, MJ Schalij, W Udayachalerm, EE van der Wall, AV Bruschke
Catheterization and Cardiovascular Diagnosis 1998
Covalent Linkage of Recombinant Hirudin to a Novel Ionic Poly(Carbonate) Urethane Polymer with Protein Binding Sites: Determination of Surface Antithrombin Activity
MD Phaneuf, M Szycher, SA Berceli, DJ Dempsey, WC Quist, FW LoGerfo
Artificial Organs 1998
UNFRACTIONATED AND LOW-MOLECULAR-WEIGHT HEPARIN
GF Pineo, RD Hull
Medical Clinics of North America 1998
Low molecular weight heparins: current use and indications
MA Quader, LS Stump, BE Sumpio
Journal of the American College of Surgeons 1998
Heparin-Induced Thrombocytopenia
DB Brieger, KH Mak, K Kottke-Marchant, EJ Topol
Journal of the American College of Cardiology 1998
Case studies in therapeutics: warfarin resistance and inefficacy in a man with recurrent thromboembolism, and anticoagulant-associated priapism
PA Routledge, HG Shetty, JP White, P Collins
British Journal of Clinical Pharmacology 1998
Pulmonary Embolism
SZ Goldhaber
New England Journal of Medicine 1998
4 Prevention of venous thromboembolism in general surgery
VV Kakkar, F Lorenzo
Baillière's Clinical Haematology 1998
Low-molecular-weight heparin for the treatment of venous thromboembolism
J Hirsh
American Heart Journal 1998
13 Heparin-induced thrombocytopenia: pathophysiology and clinical concerns
A Greinacher
Baillière's Clinical Haematology 1998
5 Heparin and low-molecular-weight heparin in the treatment of venous thromboembolism
GF Pineo, RD Hull
Baillière's Clinical Haematology 1998
Heparin and Low-Molecular-Weight Heparin
J Hirsh, TE Warkentin, R Raschke, C Granger, EM Ohman, JE Dalen
Chest 1998
Therapeutic Concentrations of Heparin Augment Platelet Activation at the Time of Coronary Angiography
TZ Naqvi, PK Shah, PA Ivey, MD Molloy, P Linn, M Linker-Israeli, B Cercek, S Kaul
Journal of cardiovascular pharmacology and therapeutics 1998
Platelet Activation With Unfractionated Heparin at Therapeutic Concentrations and Comparisons With a Low-Molecular-Weight Heparin and With a Direct Thrombin Inhibitor
Z Xiao, P Théroux
Circulation 1998
Low-Molecular-Weight Heparin: A Review of the Results of Recent Studies of the Treatment of Venous Thromboembolism and Unstable Angina
J Hirsh
Circulation 1998
Pharmacodynamic Profile of Short-term Abciximab Treatment Demonstrates Prolonged Platelet Inhibition With Gradual Recovery From GP IIb/IIIa Receptor Blockade
MA Mascelli, ET Lance, L Damaraju, CL Wagner, HF Weisman, RE Jordan
Circulation 1998
Antiplatelet Effect of Ticlopidine After Coronary Stenting
FJ Neumann, M Gawaz, T Dickfeld, A Wehinger, H Walter, R Blasini, A Schömig
Journal of the American College of Cardiology 1997
Heparin-associated Thrombocytopenia and Thrombosis
TF Slaughter, CS Greenberg
Anesthesiology 1997
Antithrombotic and Platelet Activating Effects of Heparin in Prevention of Microarterial Thrombosis
B Arnljots, P Dougan, D Bergqvist
Plastic & Reconstructive Surgery 1997
In vitro blood compatibility of functional group-grafted and heparin-immobilized polyurethanes prepared by plasma glow discharge
IK Kang, OH Kwon, MK Kim, YM Lee, YK Sung
Biomaterials 1997
The platelet proaggregating and potentiating effects of unfractionated heparin, low molecular weight heparin and heparinoid in intensive care patients and healthy controls
JK Burgess, BH Chong
European Journal of Haematology 1997
Covalent linkage of recombinant hirudin to poly(ethylene terephthalate) (Dacron): creation of a novel antithrombin surface
MD Phaneuf, SA Berceli, MJ Bide, WG Quist, FW LoGerfo
Biomaterials 1997
LOW-MOLECULAR-WEIGHT HEPARIN: Prophylaxis and Treatment of Venous Thromboembolism
GF MD, RD MD
Annual Review of Medicine 1997
Low-Molecular-Weight Heparins
AJ Wood, JI Weitz
New England Journal of Medicine 1997
BIOCHEMICAL AND PHARMACOLOGIC RATIONALE FOR THE DEVELOPMENT OF A SYNTHETIC HEPARIN PENTASACCHARIDE
JM Walenga, WP Jeske, L Bara, MM Samama, J Fareed
Thrombosis Research 1997
ANTICOAGULANT FUCOIDAN FRACTIONS FROM FUCUS VESICULOSUS INDUCE PLATELET ACTIVATION IN VITRO
J Dürig, T Bruhn, KH Zurborn, K Gutensohn, HD Bruhn, L Béress
Thrombosis Research 1997
The effect of preoperative recombinant human erythropoietin therapy on platelets and hemostasis in patients undergoing cardiac surgery
O Sowade, S Ziemer, B Sowade, W Franke, D Messinger, E Ziebell, P Scigalla, H Warnke
Journal of Laboratory and Clinical Medicine 1997
Rapid and Simple Platelet Function Assay to Assess Glycoprotein IIb/IIIa Receptor Blockade
BS Coller, D Lang, LE Scudder
Circulation 1997
Life-Threatening Coagulation Disorders in Critical Care Medicine
V Hach-Wunderle, PP Nawroth
1997
Low Molecular Weight Heparin(oid)s: Clinical Investigations and Practical Recommendations
MT Nurmohamed, H ten Cate, JW ten Cate
Drugs 1997
Disorders of platelet function
I Fuse
Critical Reviews in Oncology/Hematology 1996
Cardiopulmonary bypass in patients with heparin-induced thrombocytopenia using org 10172
MJ Wilhelm, C Schmid, D Kececioglu, T Möllhoff, H Ostermann, HH Scheld
The Annals of Thoracic Surgery 1996
Diabetic Microangiopathic Hemolytic Anemia and Thrombocytopenia With Antiphospholipid Syndrome
H Morita, T Suwa, H Daidoh, N Takeda, T Ishizuka, K Yasuda
The American Journal of the Medical Sciences 1996
Inhibition of platelet GPIIbIa in an ex vivo model of hyperacute xenograft rejection does not prolong cardiac survival time
SC Robson, VK Young, NS Cook, G Kottirsch, JB Siegel, BA Lesnikoski, D Candinas, DJ White, FH Bach
Xenotransplantation 1996
Aggregation of human platelets induced by porcine endothelial cells is dependent upon both activation of complement and thrombin generation
SC Robson, JB Siegel, BA Lesnikoski, C Kopp, D Candinas, U Ryan, FH Bach
Xenotransplantation 1996
Changes in membrane glycoproteins of circulating platelets after coronary stent implantation
M Gawaz, FJ Neumann, I Ott, A May, S Rüdiger, A Schömig
Heart (British Cardiac Society) 1996
Heparin induced thrombocytopenia
M Dryjski, H Dryjski
European Journal of Vascular and Endovascular Surgery 1996
VARIABLE INFLUENCE OF HEPARIN AND CONTRAST AGENTS ON PLATELET FUNCTION AS ASSESSED BY THE IN VITRO BLEEDING TIME
LG Melton, GJ Dehmer, DA Tate, KM Muga, A Meehan, DA Gabriel
Thrombosis Research 1996
Low-molecular-weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: Results of a meta-analysis
S Siragusa, B Cosmi, F Piovella, J Hirsh, JS Ginsberg
The American Journal of Medicine 1996
Surface-bound heparin fails to reduce thrombin formation during clinical cardiopulmonary bypass
RC Gorman, NP Ziats, AK Rao, N Gikakis, L Sun, MM Khan, N Stenach, S Sapatnekar, V Chouhan, JH Gorman, S Niewiarowski, RW Colman, JM Anderson, LH Edmunds
The Journal of Thoracic and Cardiovascular Surgery 1996
Effect of Low-Molecular-Weight Heparin (Tinzaparin) and Unfractionated Heparin on Platelet Aggregation
HB Ravn, C Bregengaard, H Vissinger, P Østergaard, J Holst, HK Nielsen, SD Kristensen, SE Husted
Clinical and Applied Thrombosis/Hemostasis 1996
THROMBIN INHIBITION IN AN EX VIVO MODEL OF PORCINE HEART XENOGRAFT HYPERACUTE REJECTION1:
SC Robson, VK Young, NS Cook, R Metternich, W Kasper-Konig, BA Lesnikoski, RN Pierson, WW Hancock, D Candinas, DJ White, FH Bach
Transplantation 1996
Management of Deep Vein Thrombosis and Pulmonary Embolism: A Statement for Healthcare Professionals From the Council on Thrombosis (in Consultation With the Council on Cardiovascular Radiology), American Heart Association
J Hirsh, J Hoak
Circulation 1996
Heparin-Coated Palmaz-Schatz Stents in Human Coronary Arteries: Early Outcome of the Benestent-II Pilot Study
PW Serruys, H Emanuelsson, W van der Giessen, AC Lunn, F Kiemeney, C Macaya, W Rutsch, G Heyndrickx, H Suryapranata, V Legrand, JJ Goy, P Materne, H Bonnier, MC Morice, J Fajadet, J Belardi, A Colombo, E Garcia, P Ruygrok, P de Jaegere, MA Morel
Circulation 1996
Lebensbedrohliche Gerinnungsstörungen in der Intensivmedizin
V Hach-Wunderle, PP Nawroth
1996
Hit, hitt, and desulfatohirudin: Look before you leap
LH Edmunds
The Journal of Thoracic and Cardiovascular Surgery 1995
The impact of heparin concentration and activated clotting time monitoring on blood conservation
GJ Despotis, JH Joist, CW Hogue, A Alsoufiev, K Kater, LT Goodnough, SA Santoro, E Spitznagel, M Rosenblum, DG Lappas
The Journal of Thoracic and Cardiovascular Surgery 1995
Reticulated platelets in uremic patients: Effect of hemodialysis and continuous ambulatory peritoneal dialysis
D Tassies, JC Reverter, A Cases, G Escolar, N Villamor, J López-Pedret, R Castillo, A Ordinas
American Journal of Hematology 1995
Acute myocardial infarction during coronary angioplasty associated with heparin-induced thrombocytopenia
BK Gupta, MP Savage, AN Brest
Catheterization and Cardiovascular Diagnosis 1995
A comparison between the use of recombinant hirudin and heparin during hemodialysis
V Wyk, PN Badenhorst, HG Luus, HF Kotzé
Kidney International 1995
Heparin Immobilized Chitosan - Poly Ethylene Glycol Interpenetrating Network: Antithrombogenicity
MS Beena, T Chandy, CP Sharma
Artificial Cells, Blood Substitutes and Biotechnology 1995
Bioavailability and pharmacokinetics of a new low molecular weight heparin (RO-11)—A three way cross-over study in healthy volunteers
L Falkon, D Sáenz-Campos, R Antonijoan, S Martín, M Barbanoj, J Fontcuberta
Thrombosis Research 1995
Heparins
J Hirsh
Fibrinolysis 1995
Heparin: Mechanism of Action, Pharmacokinetics, Dosing Considerations, Monitoring, Efficacy, and Safety
J Hirsh, CR Raschke, TE Warkentin, JE Dalen, D Deykin, L Poller
Chest 1995
Laboratory Evaluation of Platelet Dysfunction
RL Bick
Clinics in Laboratory Medicine 1995
Activated Clotting Time as an Appropriate Test to Compare Heparin and Direct Thrombin Inhibitors Such as Hirudin or Ro 46-6240 in Experimental Arterial Thrombosis
JP Carteaux, A Gast, TB Tschopp, S Roux
Circulation 1995
Effects of Recombinant Hirudin (r-Hirudin, HBW 023) on Coagulation and Platelet Activation In Vivo: Comparison With Unfractionated Heparin and a Low-Molecular-Weight Heparin Preparation (Fragmin)
S Eichinger, M Wolzt, B Schneider, M Nieszpaur-Los, H Heinrichs, K Lechner, HG Eichler, PA Kyrle
Arteriosclerosis, thrombosis, and vascular biology 1995
Cardiopulmonary Bypass
CT Mora, RA Guyton, DC Finlayson, RL Rigatti
1995
Inhibitory Effect of Clopidogrel, Vapiprost and Argatroban on the Middle Cerebral Artery Thrombosis in the Rat
K Umemura, H Kawai, H Ishihara, M Nakashima
The Japanese Journal of Pharmacology 1995
Advantageous effect of low-molecular-weight heparin administration on hepatic mitochondrial redox state
H Sasaki, T Yamaguchi, K Kumada, H Higashiyama, M Terasaki, S Mashima, A Mitsuyoshi, M Nakagami, T Morimoto, Y Shimahara, K Ozawa
Research in Experimental Medicine 1994
Mechanism of action of heparin and heparin-like antithrombotics
ST Olson, I Björk
Perspectives in Drug Discovery and Design 1994
Benestent II: Back to the Future
H Emanuelsson, WI van der GIESSEN, PW Serruys
Journal of Interventional Cardiology 1994
Interaction of heparin with synthetic antithrombin III peptide analogues
J Bae, UR Desai, A Pervin, EE Caldwell, JM Weiler, RJ Linhardt
Biochemical Journal 1994
Deep-Vein Thrombosis
EE Weinmann, EW Salzman
New England Journal of Medicine 1994
At high heparin concentrations, protamine concentrations which reverse heparin anticoagulant effects are insufficient to reverse heparin anti-platelet effects
ME Carr, SL Carr
Thrombosis Research 1994
Role of tissue factor pathway inhibitor in post surgical deep venous thrombosis (DVT) prophylaxis in patients treated with low molecular weight heparin
R Kijowski, D Hoppensteadt, J Walenga, L Borris, MR Lassen, J Fareed
Thrombosis Research 1994
Dermatan sulphate for the treatment of disseminated intravascular coagulation (DIC) in acute leukaemia: A randomised, heparin-controlled pilot study
E Cofrancesco, C Boschetti, P Leonardi, F Gianese, M Cortellaro
Thrombosis Research 1994
10 Myeloproliferative and metabolic causes
SD Wright, EG Tuddenham
Baillière's Clinical Haematology 1994
Immunochemistry Labfax
R Thorpe, B Rafferty
Immunochemistry Labfax 1994
Platelet function defects associated with hemorrhage or thrombosis
RL Bick
Medical Clinics of North America 1994
Deep vein thrombosis: Diagnosis and Management
WF Baker, RL Bick
Medical Clinics of North America 1994
Prophylaxis for the Prevention of Venous Thromboembolism after Total Knee Arthroplasty. A Comparison between Unfractionated and Low-Molecular-Weight Heparin:
P Fauno, O Suomalainen, V Rehnberg, TB Hansen, K Kroner, S Soimakallio, E Nielsen
The Journal of Bone and Joint Surgery. American volume. 1994
Pharmacology of Current and Future Antithrombotic Therapies
TH Müller, K Binder, BD Guth
Cardiology Clinics 1994
Guide to anticoagulant therapy. Part 1: Heparin. American Heart Association
J Hirsh, V Fuster
Circulation 1994
Anticoagulation
C Doutremepuich
1994
The Modern Era of Coronary Thrombolysis
RC Becker
1994
Parnaparin: A Review of its Pharmacology, and Clinical Application in the Prevention and Treatment of Thromboembolic and Other Vascular Disorders
JE Frampton, D Faulds
Drugs 1994
Heparin coating reduces blood cell adhesion to arterial filters during coronary bypass: A clinical study
JW Borowiec, A Bylock, J der Linden, S Thelin
The Annals of Thoracic Surgery 1993
Heparin-Associated Thrombocytopenia: No Association of Immune Response with HLA
A Greinacher, G Mueller-Eckhardt
Vox Sanguinis 1993
Heparin-induced thrombocytopenia in children
IA Murdoch, RM Beattie, DM Silver
Acta Paediatrica 1993
Structural characterization of heparin's binding domain for human platelets
Y Suda, D Marques, JC Kermode, S Kusumoto, M Sobel
Thrombosis Research 1993
Clinical evaluation of low-molecular-weight heparin (FR-860) on disseminated intravascular coagulation (DIC) - a multicenter co-operative double-blind trial in comparison with heparin -
N Sakuragawa, H Hasegawa, M Maki, M Nakagawa, M Nakashima
Thrombosis Research 1993
Evaluation of a low molecular weight heparin as an anticoagulant in a model of cardiopulmonary bypass surgery
MJ Koza, HL Messmore, ME Wallock, JM Walenga, R Pifarre
Thrombosis Research 1993
Comparison of the antithrombotic effects of low molecular weight heparinoid KB-101 and heparin in a rat experimental model
A Suehiro, J Imaoka, E Kakishita
General Pharmacology: The Vascular System 1993
Effects of Heparin on the Vessel Wall and Blood Cellular Elements
D Bergqvist, A Siegbahn
1993
The British Society for Haematology Guidelines on the use and monitoring of heparin 1992: second revision. BCSH Haemostasis and Thrombosis Task Force
BT Colvin, TW Barrowcliffe
Journal of clinical pathology 1993
Test Procedures for the Blood Compatibility of Biomaterials
S Dawids
1993
The Role of Platelets in Blood-Biomaterial Interactions
YF Missirlis, JL Wautier
1993
High-dose heparin suppresses platelet alpha granule secretion
MJ Rohrer, AS Kestin, PA Ellis, MR Barnard, L Rodino, WL Breckwoldt, JM Li, AD Michelson
Journal of Vascular Surgery 1992
Low molecular weight heparin for hickman catheter-induced thrombosis in thrombocytopenic patients undergoing bone marrow transplantation
PE Drakos, A Nagler, R Or, S Gillis, S Slavin, A Eldor
Cancer 1992
Future alternatives to heparin: Low-molecular-weight heparin and hirudin
CE Donayre, K Ouriel, RY Rhee, CK Shortell
Journal of Vascular Surgery 1992
Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery: a meta-analysis
MT Nurmohamed, HR Buller, E Dekker, DW Hommes, FR Rosendaal, E Briet, FR Rosendaal, JP Vandenbroucke
The Lancet 1992
Effect of heparin and enoxaparin on platelet interaction with fibrin clots
M Mirshahi, J Soria, E Neuhart, PG Steg, P Jacob, S Combe, C Soria
Thrombosis Research 1992
The effect of heparin versus citrate on blood echogenicity in vitro: The role of platelet and platelet-neutrophil aggregates
C Mahony, J Ferguson
Ultrasound in Medicine & Biology 1992
Thrombin antagonists and antiplatelet agents
RC Becker
The American Journal of Cardiology 1992
Conjunctive antithrombotic and thrombolytic therapy for acute myocardial infarction
HJ Rapold, D Collen
Fibrinolysis 1992
Acquired Platelet Function Defects
RL Bick
Hematology/Oncology Clinics of North America 1992
Antithrombotic efficacy of low-molecular-weight heparin in deep arterial injury
M Heras, JH Chesebro, MW Webster, JS Mruk, DE Grill, V Fuster
Arteriosclerosis Thrombosis and Vascular Biology 1992
Applied Therapeutics
MA Koda-Kimble, LY Young
1992
Heparin-induced thrombocytopenia and thrombosis: Reversal with streptokinase a case report and review of literature
DP Mehta, EL Yoder, J Appel, KL Bergsman
American Journal of Hematology 1991
Heparin-induced thrombocytopenia and thrombosis with spinal ischaemia — recovery of platelet count following a change to a low molecular weight heparin
N Maurin, R Biniek, B Heintz, H Kierdorf
Intensive Care Medicine 1991
Effect of heparin and prostacyclin-heparin infusion on blood coagulation in haemodialysed patients
M Kuźnifwski, W Sułowicz, J Lisiewicz
International Urology and Nephrology 1991
Drug-induced Immune Thrombocytopenia
BH Chong
Platelets 1991
Low dose heparin therapy: In vitro verification of antithrombotic effect
RY Rhee, CE Donayre, K Ouriel, DG Neschis, CK Shortell
Journal of Vascular Surgery 1991
Synthesis and antithrombogenicity of heparinized polyurethanes with intervening spacer chains of various kinds
LS Liu, Y Ito, Y Imanishi
Biomaterials 1991
Platelet Function in Uraemia
MP Gordge, GH Neild
Platelets 1991
The use of a low molecular weight heparinoid (Org 10172) for extracorporeal procedures in patients with heparin dependent thrombocytopenia and thrombosis
PA Rowlings, R Mansberg, MC Rozenberg, S Evans, B Murray
Australian and New Zealand Journal of Medicine 1991
Heparin
JA Oates, AJ Wood, J Hirsh
New England Journal of Medicine 1991
Comparative effects of heparin and LMW heparin on hemostasis
J Hirsh, MR Buchanan
Thrombosis Research 1991
Heparin and low molecular weight heparin but not hirudin stimulate platelet aggregation in whole blood from acetylsalicylic acid treated healthy volunteers
J Chen, KE Karlberg, C Sylvén
Thrombosis Research 1991
Rationale for development of low-molecular-weight heparins and their clinical potential in the prevention of postoperative venous thrombosis
J Hirsh
The American Journal of Surgery 1991
Systemic mast cell disease associated with primary mediastinal germ cell tumor
P Chariot, I Monnet, F Lelong, C Chleq, JP Droz, H Cremoux
The American Journal of Medicine 1991
Recombinant tissue-type plasminogen activator: Current concepts and guidelines for clinical use in acute myocardial infarction. Part II
RC Becker, R Harrington
American Heart Journal 1991
Newer concepts in the treatment of unstable angina pectoris
D Waters, J Lam, P Théroux
The American Journal of Cardiology 1991
Pro: Desmopressin is of value in the treatment of post-cardiopulmonary bypass bleeding
JS Shiffrin, DD Glass
Journal of Cardiothoracic and Vascular Anesthesia 1991
Heparinized Polyurethane Surface through Ionic Bonding of Heparin
R Barbucci, A Magnani, A Albanese, F Tempesti
The International Journal of Artificial Organs 1991
Blood Use in Cardiac Surgery
N Friedel, R Hetzer, D Royston
1991
Recent Developments in Toxicology: Trends, Methods and Problems
PL Chambers, CM Chambers, WD Wiezorek, S Golbs
1991
Supported Complex and High Risk Coronary Angioplasty
FA Shawl
1991
Perinatal Thrombosis and Hemostasis
S Suzuki, WE Hathaway, J Bonnar, AH Sutor
1991
The influence of preoperative anticoagulation on heparin response during cardiopulmonary bypass
W Dietrich, M Spannagl, W Schramm, W Vogt, A Barankay, JA Richter
The Journal of Thoracic and Cardiovascular Surgery 1991
Porcine heparin increases postoperative bleeding in cardiopulmonary bypass patients
LI Iverson, FG Duhaylongsod, JN Young, RR Ecker, CL Ennix, RL Moretti, M Farrar, R Hayes, J Lee, IA May
Cardiovascular Drugs and Therapy 1990
The effect of molecular weight on heparin binding to platelets
MD Horne, ES Chad
British Journal of Haematology 1990
Inhibition of coagulation and platelet adhesion to extracellular matrix by unfractionated heparin and a low molecular weight heparin
K Krupinski, M Basic-Micic, E Lindhoff, HK Breddin
Blut 1990
Pathophysiology of Cardiopulmonary Bypass: Current Issues
JR Utley
Journal of Cardiac Surgery 1990
Arteriosklerose
A Maelicke
Nachrichten aus Chemie, Technik und Laboratorium 1990
Heparin-induced platelet aggregation. II. Dose/response relationships for two low molecular weight heparin fractions (CY 216 and CY 222)
LD Brace, J Fareed
Thrombosis Research 1990
The effect of dermatan sulfate on in vitro human plasma coagulation, platelet aggregation and βTG/PF4 release
E Cofrancesco, M Colombi, F Gianese, M Cortellaro
Thrombosis Research 1990
The effect of heparin on multiple organ failure and disseminated intravascular coagulation in a sepsis model
T Tanaka, T Tsujinaka, J Kambayashi, M Higashiyama, M Yokota, M Sakon, T Mori
Thrombosis Research 1990
Clinical experience with low molecular weight heparins
GG Nenci, G Agnelli
Thrombosis Research 1990
Thrombocytopenia in the critically ill patient
DL Bogdonoff, ME Williams, DJ Stone
Journal of Critical Care 1990
2 Mechanisms of action of low molecular weight heparins and heparinoids
FA Ofosu, TW Barrowcliffe
Baillière's Clinical Haematology 1990
White clot syndrome: A serious complication of heparin therapy
JC Chang
Postgraduate Medicine 1990
Platelet Inhibitor Therapy: Agents and Clinical Implications
MW Webster, JH Chesebro, V Faster
Hematology/Oncology Clinics of North America 1990
Heparin and Platelets
TE Warkentin, JG Kelton
Hematology/Oncology Clinics of North America 1990
Dose- and shear rate-dependent effects of heparin on thrombogenesis induced by rabbit aorta subendothelium exposed to flowing human blood
W Inauen, HR Baumgartner, T Bombeli, A Haeberli, PW Straub
Arteriosclerosis (Dallas, Tex.) 1990
Heparin: What Is It? How Does It Work?
BS Schwartz
Clinical Cardiology 1990
Unstable Angina
W Bleifeld, CW Hamm, E Braunwald
1990
Inhibition of coagulation and platelet adhesion to extracellular matrix by unfractionated heparin and a low molecular weight heparin
K Krupinski, M Basic-Micic, E Lindhoff, HK Breddin
Blut Zeitschrift für die Gesamte Blutforschung 1990
Pharmacotherapeutic Aspects of Unfractionated and Low Molecular Weight Heparins:
M Verstraete
Drugs 1990
Platelet inhibitor agents in cardiovascular disease: An update
B Stein, V Fuster, DH Israel, M Cohen, L Badimon, JJ Badimon, JH Chesebro
Journal of the American College of Cardiology 1989
The mechanism of heparin-induced platelet aggregation
BH Chong, F Ismail
European Journal of Haematology 1989
Heparin-induced thrombocytopenia
BH Chong, MC Berndt
Blut 1989
In vitro platelet interactions with a heparin-polyvinyl alcohol hydrogel
CH Cholakis, MV Sefton
Journal of Biomedical Materials Research 1989
Platelet adhesion onto protein-coated and uncoated polyetherurethaneurea having tertiary amino groups in the substituents and its derivatives
Y Ito, M Sisido, Y Imanishi
Journal of Biomedical Materials Research 1989
A prospective randomized trial of low molecular weight heparin-DHE and conventional heparin-DHE (with acenocoumarol) in patients undergoing gynaecological surgery
RA Steiner, K Keller, T L�scher, WE Schreiner
Archives of Gynecology and Obstetrics 1989
Comparison of Antiplatelet Aggregatory and Antithrombotic Activity of Low Molecular Weight RD Heparin with Heparin
RL Fenichel, W Carmint, B Small, J Willis
Annals of the New York Academy of Sciences 1989
Thromboembolic problems in pregnancy
IA Greer
Fetal and Maternal Medicine Review 1989
PROTEIN C DEFICIENCY AND THROMBOTIC COMPLICATIONS AFTER LIVER TRANSPLANTATION IN CHILDREN
MD Stringer, E Melissari, VV Kakkar, KC Tan
The Lancet 1989
The ex Vivo Correlate of the Antithrombotic Action of Heparin
HC Hemker, S Béguin, J Pieters, T Lindhout
Annals of the New York Academy of Sciences 1989
Safety and pharmacokinetics of the low molecular weight heparinoid Org 10172 administered to healthy elderly volunteers
JC Stiekema, HP Wijnand, TG van Dinther, HC Moelker, J Dawes, A Vinchenzo, H Toeberich
British Journal of Clinical Pharmacology 1989
Measuring platelet function with platelet shape change, an early event in aggregation
DO Beaumont, KW Whitten, RG Mock, CW Slattery
Thrombosis Research 1989
Phlegmasia Cerulea Dolens and Its Association with Hypercoagulable States: Case Reports
DJ Cohen, R Briggs, HD Head, CW Acher
Angiology 1989
Effects of Glycosaminoglycans and Protamine Chloridrate on Platelet Aggregation Induced by Collagen and Thrombin
G Luzzatto, R Paolini, F Stevanato, P Simioni, G Cella
Angiology 1989
Recurrent ischemic events after successful thrombolysis in acute myocardial infarction. The Achilles' heel of thrombolytic therapy
CW White
Circulation 1989
Preservation and structural adaptation of endothelium over experimental foam cell lesions. Quantitative ultrastructural study
KE Taylor, S Glagov, CK Zarins
Arteriosclerosis (Dallas, Tex.) 1989
Heparin-induced thrombocytopenia
BH Chong, MC Berndt
Blut Zeitschrift für die Gesamte Blutforschung 1989
A prospective randomized trial of low molecular weight heparin-DHE and conventional heparin-DHE (with acenocoumarol) in patients undergoing gynaecological surgery
RA Steiner, K Keller, T Lscher, WE Schreiner
Archives of Gynecology and Obstetrics 1989
Unresolved clinical pharmacologic questions in thrombolytic therapy for acute myocardial infarction
S Sherry
Journal of the American College of Cardiology 1988
Comparison of low molecular weight heparin to standard heparin in hemodialysis/hemofiltration
J Schrader, W Stibbe, VW Armstrong, M Kandt, R Muche, H Köstering, D Seidel, F Scheler
Kidney International 1988
Impairment of primary haemostasis by low molecular weight heparins in rats
A Borowska, D Lauri, A Maggi, E Dejana, G Gaetano, MB Donati, J Pangrazzi
British Journal of Haematology 1988
Comparison of a low molecular weight heparin and unfractionated heparin for the prevention of deep vein thrombosis in patients undergoing abdominal surgery
A Encke, K Breddin
British Journal of Surgery 1988
Clinical studies with low-molecular-weight heparin(oid)s: An interim analysis
HT Gate, CP Henny, JW Cate, HR Büller
American Journal of Hematology 1988
Heparin therapy for venous thrombosis and pulmonary embolism
GE Raskob, RD Hull, CJ Carter
Blood Reviews 1988
In vitro platelet adhesion and in vivo antithrombogenicity of heparinized polyetherurethaneureas
Y Ito, Y Imanishi
Biomaterials 1988
Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone
SR Hanson, LA Harker
Proceedings of the National Academy of Sciences 1988
Characterization of platelet binding of heparins and other glycosaminoglycans
M Sobel, B Adelman
Thrombosis Research 1988
Heparin binding to normal and abnormal platelets
MD Horne
Thrombosis Research 1988
Observations on human platelet aggregation in native whole blood: Synergism and sensitivity to aggregating agents in vitro
DG Boyd, RB Davis
Thrombosis Research 1988
Potentiation of platelet interaction with collagen substrates by heparin is insensitive to aspirin
AV Mazurov, VE Sinitsyn, VS Repin
Thrombosis Research 1988
Heparin-Induced Thrombocytopenia and Thrombosis in Ischemic Stroke
JL Atkinson, TH SUNDT, FJ Kazmier, EW Bowie, JP Whisnant
Mayo Clinic Proceedings 1988
The Antithrombotic Activity and Pharmacokinetics of Enoxaparine, A Low Molecular Weight Heparin, In Humans Given Single Subcutaneous Doses of 20 to 80 mg
AM Frydman, L Bara, YH Roux, M Woler, F Chauliac, MM Samama
The Journal of Clinical Pharmacology 1988
Aspirin, Heparin, or Both to Treat Acute Unstable Angina
P Théroux, H Ouimet, J McCans, JG Latour, P Joly, G Lévy, E Pelletier, M Juneau, J Stasiak, P deGuise, GB Pelletier, D Rinzler, DD Waters
New England Journal of Medicine 1988
Thrombocytopenia and Drugs
P Handagama, BF Feldman
Veterinary Clinics of North America Small Animal Practice 1988
Importance of adequate heparin dosage in arterial angioplasty in a porcine model
M Heras, JH Chesebro, WJ Penny, KR Bailey, JY Lam, DR Holmes, GS Reeder, L Badimon, V Fuster
Circulation 1988
Haemodialysis
GR Catto
1988
Platelet-Vessel Wall Interactions
RM Pittilo, SJ Machin
1988
Acquired Disorders of Platelet Functionb
LA Harker
Annals of the New York Academy of Sciences 1987
Drug-mediated thrombocytopenia
MC Berndt, PA Castaldi
Blood Reviews 1987
Interactions between prostacyclin analogue ZK 36374 and heparin in their effects upon platelet function
DA Yardumian, K O'Flynn, DC Linch, SJ Machin
British Journal of Haematology 1987
Comparison of the platelet pro-aggregatory effect of conventional unfractionated heparins and a low molecular weight heparin fraction (CY 222)
MA Barradas, DP Mikhailidis, O Epemolu, JY Jeremy, V Fonseca, P Dandona
British Journal of Haematology 1987
Antithrombotic activity of a synthetic heparin pentasaccharide in a rabbit stasis thrombosis model using different thrombogenic challenges
JM Walenga, M Petitou, JC Lormeau, M Samama, J Fareed, J Choay
Thrombosis Research 1987
A kinetic study on the effects of anticoagulants on the interaction of fibrinogen and thrombin
E Nakanishi, H Sato, A Nakajima
Journal of Biomedical Materials Research 1987
Acute Thrombocytopenia and Thrombosis
JG Kelton, WG Murphy
Annals of the New York Academy of Sciences 1987
Effect of heparin on platelet count and platelet aggregation
AM Shojania, G Turnbull
American Journal of Hematology 1987
Thromboresistance of bulk heparinized catheters in human
R Eloy, J Belleville, J Paul, C PusinÉri, J Baguet, MC Rissoan, D Cathignol, P Ffrench, D Ville, M Tartullier
Thrombosis Research 1987
Immune Endothelial-Cell Injury in Heparin-Associated Thrombocytopenia
DB Cines, A Tomaski, S Tannenbaum
New England Journal of Medicine 1987
A 51-year-old man requires a heart transplant using cardiopulmonary bypass and has a heparin-related immune thrombocytopenia
MB Howie, GJ Suntay, DP Myerowitz, TA Galbraith, JT Brandt, VP Addonizio, N Ellison
Journal of Cardiothoracic Anesthesia 1987
Antithrombogenic Heparin-Bound Polyurethanes
Y Ito
Journal of Biomaterials Applications 1987
Heparinization of Medical Grade Polyurethanes
R Eloy, J Belleville, MC Rissoan, J Baguet
Journal of Biomaterials Applications 1987
Aspirin and dipyridamole in the prevention of acute coronary thrombosis complicating coronary angioplasty
ES Barnathan, JS Schwartz, L Taylor, WK Laskey, JP Kleaveland, WG Kussmaul, JW Hirshfeld
Circulation 1987
Prostacyclin and Its Stable Analogue Iloprost
RJ Gryglewski, G Stock
1987
Cerebral Ischemia and Hemorheology
A Hartmann, W Kuschinsky
1987
Treatment of acute pulmonary embolism by a low molecular weight heparin fraction. A preliminary study
Y Huet, M Gouault-Heilmann, G Contant, C Brun-Buisson
Intensive Care Medicine 1987
Interaction of a new low molecular weight heparin (OP/LMWH) with human platelets
R Mastacchi, M Barbanti, P Bianchini, B Osima
Agents and Actions 1986
Drug-induced thrombocytopenia
PJ Handagama, BF Feldman
Veterinary Research Communications 1986
Pharmacology of platelet inhibitors
LA Harker, V Fuster
Journal of the American College of Cardiology 1986
The haemorrhagic and antithrombotic effects of dermatan sulphate
F Fernandez, JV Ryn, FA Ofosu, J Hirsh, MR Buchanan
British Journal of Haematology 1986
Different platelet specificities of heparin-dependent platelet aggregating factors in heparin-associated immune thrombocytopenia
SL Pfueller, R David
British Journal of Haematology 1986
Synthesis and antithrombogenicity of anionic polyurethanes and heparin-bound polyurethanes
Y Ito, M Sisido, Y Imanishi
Journal of Biomedical Materials Research 1986
In vitro bioactivity of a synthesized prostaglandin E1-heparin conjugate
H Jacobs, SW Kim
Journal of Pharmaceutical Sciences 1986
Heparin fractions and analogues: a new therapeutic possibility for thrombosis
D Prost
Trends in Pharmacological Sciences 1986
Hemocompatible Polymers: Preparation and Properties
JE Wilson
Polymer-Plastics Technology and Engineering 1986
Effect of heparin on platelet aggregation inhibited by PGI2, trifluoperazine and verapamil
DR Weber, WK Nichols, SF Mohammad
Thrombosis Research 1986
Antithrombotic and haemorrhagic effects of synthetic and naturally occurring thrombin inhibitors
B Kaiser, F Markwardt
Thrombosis Research 1986
Heparin-induced platelet aggregation: Dose/response relationships for a low molecular weight heparin derivative (pk 10169) and its subfractions
LD Brace, J Fareed
Thrombosis Research 1986
Comparison of the effects of low molecular weight heparin and unfractionated heparin on activation of human platelets in vitro
J Westwick, MF Scully, C Poll, VV Kakkar
Thrombosis Research 1986
Spontaneous platelet aggregation in heparinised blood during pregnancy
ME Burgess-Wilson, R Morrison, S Heptinstall
Thrombosis Research 1986
Aggregation of human neutrophils by heparin
ER Lazarowski, JA Santané, NH Behrens, JC Avalos
Thrombosis Research 1986
Hemorrhagic doses of heparin and other glycosaminoglycans induce a platelet defect
F Fernandez, P N'guyen, JV Ryn, FA Ofosu, J Hirsh, MR Buchanan
Thrombosis Research 1986
Comparison of the haemorrhagic effects of unfractionated heparin and a low molecular weight heparin fraction (cy 216) in rabbits
C Doutremepuich, F Toulemonde, F Bousquet, F Bonini
Thrombosis Research 1986
Heparin-induced platelet aggregation and its inhibition by antagonists of the thromboxane pathway
E Cofrancesco, M Colombi, C Fowst, EM Pogliani
Thrombosis Research 1986
Anesthetics and anticoagulants used in the preparation of rat platelet-rich-plasma alter rat platelet aggregation
SD Dwyer, KM Meyers
Thrombosis Research 1986
Effects of heparin on prostacyclin binding and platelet adenylate cyclase activity stimulated by iloprost and forskolin
K Jaschonek, C Faul, W Daiss, H Weisenbergerl
Prostaglandins, Leukotrienes and Medicine 1986
Fibrin formation and platelet aggregation in patients with acute myocardial infarction: Effects of intravenous and subcutaneous low-dose heparin
A Gallino, A Haeberli, T Hess, G Mombelli, PW Straub
American Heart Journal 1986
Low-Molecular-Weight Heparin
EW Salzman
New England Journal of Medicine 1986
Clinical Efficacy of Heparin Fractions: Issues and Answers
HL Messmore, J Hirsh
Critical Reviews in Clinical Laboratory Sciences 1986
Heparin: Do We Understand Its Antithrombotic Actions?
DB Cines
Chest 1986
Case Report: Treatment of Silastic Catheter-Induced Central Vein Septic Thrombophlebitis
MS Topiel, RT Bryan, CM Kessler, GL Simon
The American Journal of the Medical Sciences 1986
Low Molecular Weight Heparins and Heparinoid, a Recent Development in Anticoagulant Treatment: Application in Hemodialysis
JW Cate, JM Wilmink
The International Journal of Artificial Organs 1986
Thrombosis and Thrombolysis
EI Chazov, VN Smirnov
1986
Interactions of platelets with standard heparin and low molecular weight fractions
C Soria, J Soria, FW Dunn, A Thomaidis, G Tobelem, JP Caen
The Medical Journal of Australia 1986
Heparin‐induced thrombocytopenia
D Green
The Medical Journal of Australia 1986
Heparin‐like substances: acidic mucopolysaccharides from sea cucumbers and their biological effects
C Ruan, Q Wu, Z Wang, J Soria, C Soria, JP Caen
The Medical Journal of Australia 1986
Anwendung von niedermolekularem Heparin bei Hämodialysepatienten
J Schrader, J Rieger, H Müschen, W Stibbe, H Köstering, P Kramer, F Scheler
Klinische Wochenschrift 1985
Low molecular weight heparin in hemodialysis and hemofiltration patients
J Schrader, R Valentin, HJ Tönnis, U Hildebrand, W Stibbe, VW Armstrong, M Kandt, H Köstering, E Quellhorst
Kidney International 1985
Heparin-mediated neutralization of platelet antiaggregatory activity of prostacyclin (PGI2): Studies on mechanism
SR Saba, HI Saba
American Journal of Hematology 1985
Heparin-induced platelet aggregation in anorexia nervosa and in severe peripheral vascular disease
DP Mikhailidis, MA Barradas, JY Jeremy, L Gracey, A Wakeling, P Dandona
European Journal of Clinical Investigation 1985
Blood compatibility of heparinized polyurethanes
PW Heyman, SW Kim
Die Makromolekulare Chemie 1985
Efficacy and safety of low-molecular-weight heparin (CY216) in preventing postoperative venous thrombo-embolism: A co-operative study
VV Kakkar, WJ Murray
British Journal of Surgery 1985
Complications of heparin administration in normal individuals
KA Schwartz, G Royer, DB Kautman, JA Penner
American Journal of Hematology 1985
Monomeric and Polymeric Collagen-Induced Platelet Aggregation in Citrated and Heparinized Platelet-Rich Plasma
G Csako, EA Suba, A Herp
Connective Tissue Research 1985
Heparin-induced platelet aggregation is inhibited by antagonists of the thromboxane pathway
LD Brace, S Issleib, J Fareed
Thrombosis Research 1985
Heparin does not interfere with prostacyclin and prostaglandin D2 binding to platelets
A Fortini, PA Modesti, R Abbate, GF Gensini, GG Serneri
Thrombosis Research 1985
Anticoagulant effects of a low molecular weight heparinoid (ORG 10172) in human volunteers and haemodialysis patients
H Cate, CP Henny, JW Cate, HR Büller, MC Mooy, S Surachno, JM Wilmink
Thrombosis Research 1985
Hemodialysis-associated platelet activation and thrombocytopenia
RM Hakim, AI Schafer
The American Journal of Medicine 1985
Small heparin fragments regulate the amplification pathway of complement
MD Sharath, ZM Merchant, YS Kim, KG Rice, RJ Linhardt, JM Weiler
Immunopharmacology 1985
Modifications hématologiques induites par la circulation extracorporelle
A Watel, D Mathieu, A Pol, P Dequiedt, G Soots, A Cosson
Annales Françaises d’Anesthésie et de Réanimation 1985
Inhibition of human and guinea pig complement by heparin fractions differing in affinity for antithrombin III or in average molecular weight
HP Erke
International Journal of Immunopharmacology 1985
In vivo activity of a new heparinoid
PA Ockelford, CJ Carter, J Hirsh
Pathology 1985
The heparin induced thrombosis — thrombocytopenia syndrome (H.I.T.T.S.): A review
CK Arthur, JP Isbister, EM Aspery
Pathology 1985
Heparin: Applications and Future Prospects
D Quick, AA Trowbridge
Chest 1985
Clinical efficacy of low molecular weight heparin in postoperative thrombosis prophylaxis
U Schmitz-Huebner, H Bünte, G Freise, B Reers, C Rüschemeyer, R Scherer, H Schulte, J Loo
Klinische Wochenschrift 1984
Mechanism and characteristics of platelet activation by haematin
SM Neely, DV Gardner, N Reynolds, D Green, C Tšao
British Journal of Haematology 1984
Use of a heparinoid in patients with hemorrhagic stroke and thromboembolic disease
H Ten, CP Henny, HR B�ller, JW Ten, HN Magnani
Annals of Neurology 1984
Structural determinants of the capacity of heparin to inhibit the proliferation of vascular smooth muscle cells
JJ Castellot, MJ Karnovsky, DL Beeler, RD Rosenberg
Journal of Cellular Physiology 1984
Effects of low-molecular-weight heparin on platelets as compared with commercial heparin
G Cella, N Scattolo, G Luzzatto, A Girolami
Research in Experimental Medicine 1984
Effect of heparin on platelet aggregation
HI Saba, SR Saba, GA Morelli
American Journal of Hematology 1984
Interactions of human platelets with insoluble anticoagulant modified polystyrene resins
C Fougnot, J Lindon, L Kirshner, EW Sajzman, M Jopzefowicz
Biomaterials 1984
Interaction of antithrombin III with preadsorbed albumin-heparin conjugates
WE Hennink, CD Ebert, SW Kim, W Breemhaar, A Bantjes, J Feijen
Biomaterials 1984
Increased sensitivity of arachidonic acid-induced platelet aggregation in the presence of carbon dioxide
PJ Kerry, CJ Paton
British Journal of Pharmacology 1984
Appearance of platelet-clumping activity in heparinized plasma after acidification — it's mainly due to aggregation of fibrinogen
N Yamamoto, K Tanoue, H Yamazaki
Thrombosis Research 1984
Platelet activation caused by cardiac catheter blood collection, and its prevention
M J.Mant, C T.Kappagoda, R F.Taylor, J E.Quinlan
Thrombosis Research 1984
In vitro evaluation of a biologic graft surface. Effect of treatment with conventional and low molecular weight (LMW) heparin
CG Björck, D Bergövist, CO Esquivel, R Larsson, Y Rudsvik
Thrombosis Research 1984
A comparison of the anti thrombotic and haemorrhagic effects of low molecular weight heparin fractions: The influence of the method of preparation
JF Cade, MR Buchanan, B Boneu, P Ockelford, CJ Carter, AL Cerskus, J Hirsh
Thrombosis Research 1984
THE THROMBORESISTANCE OF A HEPARIN-POLYVINYL ALCOHOL HYDROGEL†
MV Sefton, WF Ip, G Rollason, MW Hatton, W Zingg
Chemical Engineering Communications 1984
Structural studies on heparin. Tetrasaccharides obtained by heparinase degradation
A Linker
Carbohydrate Research 1984
Heterogeneity of heparin lots associated with thrombocytopenia and thromboembolism
RB Stead, AI Schafer, RD Rosenberg, RI Handin, M Josa, SF Khuri
The American Journal of Medicine 1984
Thrombocytopenia in a Prospective, Randomized, Double-Blind Trial of Bovine and Porcine Heparin
D Green, GJ Martin, SH Shoichet, N Debacker, JS Bomalaski, RN Lind
The American Journal of the Medical Sciences 1984
Heparin-Induced Thrombocytopenia-Association with a Platelet Aggregating Factor and Cross-Sensitivity to Bovine and Porcine Heparin
DR Guay, A Richard
1984
Controlling Anticoagulation in Extracorporeal Blood Circuits (hemoperfusion)
L Mor, S Sideman, M Mihich, A Tzipiniuk, S Lupovich, JM Brandes
The International Journal of Artificial Organs 1984
Effect of heparin bonding on catheter-induced fibrin formation and platelet activation
AB Nichols, J Owen, BA Grossman, JJ Marcella, LN Fleisher, MM Lee
Circulation 1984
Biomaterials in Artificial Organs
JP Paul, JD Gaylor, JM Courtney, T Gilchrist
1984
Technical Considerations for Platelet Aggregation and Related Problems
ML Tiffany, RL Henry
Critical Reviews in Clinical Laboratory Sciences 1983
ASPIRIN PREVENTS HEPARIN-INDUCED PLATELET AGGREGATION IN VIVO
PA Janson, JL Moake, G Carpinito
British Journal of Haematology 1983
Normal and low molecular weight heparins: interaction with human platelets
F Fabris, F Fussi, A Casonato, L Visentin, M Randi, MR Smith, A Girolami
European Journal of Clinical Investigation 1983
Synergistic effect of heparin and chemotactic factor on polymorphonuclear leukocyte aggregation and degranulation
MS Cairo, J Allen, C Higgins, RL Baehner, LA Boxer
The American Journal of Pathology 1983
The effects of antithrombin III, heparin and a novel heparinoid infusions on the bleeding tendency using an experimental model in the rat
HR Büller, PM Hobbelen, AW Princen, HC Moelker, JW Cate
Thrombosis Research 1983
Anticoagulant effects of two types of low molecular weight heparin administered subcutaneously
D Bergqvist, U Hedner, E Sjörin, E Holmer
Thrombosis Research 1983
Fibrinogen binding on human platelets. Influence of different heparins and of pentosane polysulfate
F Dunn, J Soria, C Soria, A Thomaidis, G Tobelem, JP Caen
Thrombosis Research 1983
Myocardial Infarction and Cardiac Death
WH Frishman, EH Sonnenblick
Myocardial Infarction and Cardiac Death 1983
Biology and therapeutic potential of prostacyclin
S Moncada
Stroke; a journal of cerebral circulation 1983
Thrombocytopenia Due to Non-immune Platelet Destruction
JM Harlan
Clinics in Haematology 1983
Acquired Qualitative Platelet Disorders
AK Rao, PN Walsh
Clinics in Haematology 1983
How safe is heparin?
WR Pitney
The Medical Journal of Australia 1983
HEPARIN-INDUCED THROMBOCYTOPENIA: ASSOCIATION OF THROMBOTIC COMPLICATIONS WITH HEPARIN-DEPENDENT IgG ANTIBODY THAT INDUCES THROMBOXANE SYNTHESIS AND PLATELET AGGREGATION
BH Chong, WR Pitney, PA Castaldi
The Lancet 1982
Eighth Gaddum Memorial Lecture. University of London Institute of Education, December 1980. Biological importance of prostacyclin
S Moncada
British Journal of Pharmacology 1982
Immobilized heparin: Spacer arm effects on biological interactions
CD Ebert, KS Wan
Thrombosis Research 1982
Effect of heparin on platelet monolayer adhesion, aggregation and production of malondialdehyde
JA Davies, VC Menys
Thrombosis Research 1982
Heparin-associated thrombocytopenia. In vitro effects of different molecular weight heparin fractions
MG Huisse, MC Guillin, A Bezeaud, F Toulemonde, M Kitzis, B Andreassian
Thrombosis Research 1982
Interaction of heparin and heparin fractions with human platelets
R Mastacchi, L Stanzani, M Barbanti, L Montecchi, P Bianchini
Thrombosis Research 1982
A low molecular weight heparin compared with unfractionated heparin
DP Thomas, RE Merton
Thrombosis Research 1982
A novel anti-thrombotic heparinoid (ORG 10172) devoid of bleeding inducing capacity: A survey of its pharmacological properties in experimental animal models
DG Meuleman, PM Hobbelen, G Dedem, HC Moelker
Thrombosis Research 1982
On the mechanism of heparin-induced potentiation of platelet aggregation
M Yamamoto, K Watanabe, Y Ando, H Iri, H Handa, Y Yoshii, M Imai, K Sugiura, Y Ikeda
Thrombosis Research 1982
Comparison of the in vivo hemorrhagic and antithrombotic effects of a low antithrombin-iii affinity heparin fraction
PA Ockelford, CJ Carter, A Cerskus, CA Smith, J Hirsh
Thrombosis Research 1982
Comparison between commercial heparin, low molecular weight heparin and pentosan polysulfate on hemostasis and platelets in vivo
CO Esquivel, D Bergqvist, CG Björck, B Nilsson
Thrombosis Research 1982
Potentiation of endoperoxide analog-induced platelet aggregation by heparin
P Mehta, J Mehta
Thrombosis Research 1982
EIGHTH GADDUM MEMORIAL LECTURE UNIVERSITY OF LONDON INSTITUTE OF EDUCATION DECEMBER 1980: BIOLOGICAL IMPORTANCE OF PROSTACYCLIN
S Moncada
British Journal of Pharmacology 1982
Prostacyclin substitution for heparin in long-term hemodialysis
MC Smith, K Danviriyasup, JW Crow, AE Cato, GD Park, A Hassid, MJ Dunn
The American Journal of Medicine 1982
Biochemical Immunological Pharmacology
PE Lipsky
Biochemical Immunological Pharmacology 1982
Pathobiology of the Endothelial Cell
SA Stalcup, GM Turino, RB Mellins
Pathobiology of the Endothelial Cell 1982
Fulminant hepatic failure and artificial liver support
AE Gimson, R Ede, S Braude, RD Hughes, PJ Langley, R Williams
Gastroenterologia Japonica 1982
Fortschritte in der Kardiologie
W Schaper, MG Gottwik
1982
Structural Determinants of the Capacity of Heparin to Inhibit the Formation of the Human Amplification C3 Convertase
MD Kazatchkine, DT Fearon, DD Metcalfe, RD Rosenberg, KF Austen
Journal of Clinical Investigation 1981
In vitro Methods and the Study of Platelet Mechanisms
MA Packham, JF Mustard
Vox Sanguinis 1981
HEPARIN AND OTHER SULFATED POLYANIONS: THEIR INTERACTION WITH THE BLOOD PLATELET*
ML Tiffany, JA Penner
Annals of the New York Academy of Sciences 1981
Patency of Heparinized SBS Shunts at High Shear Rates
MV Sefton, W Zingg
Artificial Cells, Blood Substitutes and Biotechnology 1981
Thrombosis: its role and prevention in cardiovascular events--Part I. Concepts of thrombogenesis and its prevention
LA Harker
The Western journal of medicine 1981
Disorders of platelet function: mechanisms, diagnosis and management
LB Huebsch, LA Harker
The Western journal of medicine 1981
Immunoglobulin-sulfated polysaccharide interactions. Binding of agaropectin and heparin by human IgG proteins
DE Levy, AA Horner, A Solomon
Journal of Experimental Medicine 1981
Inhibition of platelet activation by prostacyclin: Possible consequences in coagulation and anticoagulation
S Bunting, PM Simmons, S Moncada
Thrombosis Research 1981
Platelet reactivity in patients with degenerated porcine bioprosthetic valves
JM Riddle, DJ Magilligan, PD Stein
Thrombosis Research 1981
Heparin opposes prostanoid and non-prostanoid platelet inhibitors by direct enhancement of aggregation
DE MacIntyre, RI Handin, R Rosenberg, EW Salzman
Thrombosis Research 1981
Heparinized Polymers as Thromboresistant Biomaterials
JE Wilson
Polymer-Plastics Technology and Engineering 1981
A comparison of prostacyclin and heparin on hemodialyses in dogs
M Gross, H Bush, H McTigue, RJ Hamburger, W Flamenbaum
Prostaglandins 1981
Prostacyclin and Blood Coagulation:
S Moncada, JR Vane
Drugs 1981
THROMBOSIS AND THROMBOCYTOPENIA INDUCED BY HEPARIN
L Carreras
Scandinavian Journal of Haematology 1980
EDITORIAL
IW Percy-Robb, ND Finlayson, MF Oliver
European Journal of Clinical Investigation 1980
Inactivation of thrombin by antithrombin III on a heparinized biomaterial
MF Goosen, MV Sefton, MW Hatton
Thrombosis Research 1980
Heparin-Associated Thrombocytopenia
DB Cines, P Kaywin, M Bina, A Tomaski, AD Schreiber
New England Journal of Medicine 1980
Heparin-Associated Thrombocytopenia: A Comparison of Three Heparin Preparations
WR Bell, RM Royall
New England Journal of Medicine 1980
Pulmonary thromboembolism: 2. New trends in prophylaxis and therapy
JC Giudice, HJ Komansky, J Kaufman
Postgraduate Medicine 1980
Clinical Pharmacology & Therapeutics
P Turner, C Padgham, A Hedges
Clinical Pharmacology & Therapeutics 1980
Antithrombotic Drugs in Relation to Prostaglandin Metabolism
J Ogrady, S Bunting, S Moncada
Clinics in Haematology 1980
Replacement of Renal Function by Dialysis
W Drukker, FM Parsons, JF Maher
1979
Annotation
B Bennett
British Journal of Haematology 1974
Prostaglandins and the Kidney
JC Mcgiff, HD ITSKOVITZ
Circulation research 1973
Hematology
JJ Shea, JJ Shea
The Laryngoscope 1949

← Previous 1 2 … 13 14 15 … 18 19 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

Referenced in 7 patents
Referenced in 3 clinical guideline sources
61 readers on Mendeley
See more details