l-Leucine was administered as a primed continuous 3-4-h infusion in nonobese and obese subjects in the postabsorptive state and for 12 h in obese subjects after a 3-day and 4-wk fast. In nonobese and obese subjects studied in the post-absorptive state, the leucine infusion resulted in a 150-200% rise in plasma leucine above preinfusion levels, a small decrease in plasma glucose, and unchanged levels of plasma insulin and glucagon and blood ketones. Plasma isoleucine (60-70%) and valine (35-40%) declined to a greater extent than other amino acids (P < 0.001).
Robert S. Sherwin
Title and authors | Publication | Year |
---|---|---|
Comprehensive Physiology
SN Cheuvront, RW Kenefick |
Comprehensive Physiology | 2014 |
Nutrition in the Prevention and Treatment of Abdominal Obesity
FP de Heredia, M Garaulet |
Nutrition in the Prevention and Treatment of Abdominal Obesity | 2014 |
Mitochondrial GTP Insensitivity Contributes to Hypoglycemia in Hyperinsulinemia Hyperammonemia by Inhibiting Glucagon Release
RG Kibbey, CS Choi, HY Lee, O Cabrera, RL Pongratz, X Zhao, AL Birkenfeld, C Li, PO Berggren, C Stanley, GI Shulman |
2014 |