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Citations to this article

Antihemophilic Factor Antigen. LOCALIZATION IN ENDOTHELIAL CELLS BY IMMUNOFLUORESCENT MICROSCOPY
Leon W. Hoyer, … , Rene P. de los Santos, John R. Hoyer
Leon W. Hoyer, … , Rene P. de los Santos, John R. Hoyer
Published November 1, 1973
Citation Information: J Clin Invest. 1973;52(11):2737-2744. https://doi.org/10.1172/JCI107469.
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Research Article Article has an altmetric score of 3

Antihemophilic Factor Antigen. LOCALIZATION IN ENDOTHELIAL CELLS BY IMMUNOFLUORESCENT MICROSCOPY

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Abstract

The tissue localization of antihemophilic factor (AHF, Factor VIII) has been determined by immunofluorescent studies using monospecific rabbit antibody to human AHF. Specific staining demonstrating AHF antigens has been identified in endothelial cells of a wide range of human tissues. The staining pattern was observed in endothelial cells of arteries, capillaries, and veins as well as the cells lining hepatic and splenic sinusoids. Specific fluorescence was limited to these endothelial cells in sections of kidney, liver, spleen, lymph node, cardiac and smooth muscle, thyroid, umbilical cord, and skin. Absorption studies established that the staining was specific for cells in which there were proteins that had AHF antigens. The demonstration of fluorescence within the cytoplasm of endothelial cells suggests that these cells synthesize proteins that have AHF antigens.

Authors

Leon W. Hoyer, Rene P. de los Santos, John R. Hoyer

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Total citations by year

Year: 2022 2021 2018 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 1980 1979 1978 1977 1976 1975 1974 1973 1965 Total
Citations: 1 1 3 1 1 3 3 5 2 5 1 1 5 2 1 3 4 7 5 2 8 11 5 9 9 9 10 13 20 15 24 19 25 28 21 17 8 6 9 11 9 7 11 5 1 1 367
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Citations to this article in year 2012 (3)

Title and authors Publication Year
AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension
RJ Teng, J Du, AJ Afolayan, A Eis, Y Shi, GG Konduri
American journal of physiology. Lung cellular and molecular physiology 2012
Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension
RJ Teng, J Du, S Welak, T Guan, A Eis, Y Shi, GG Konduri
American journal of physiology. Lung cellular and molecular physiology 2012
Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension
RJ Teng, J Du, S Welak, T Guan, A Eis, Y Shi, GG Konduri
American journal of physiology. Lung cellular and molecular physiology 2012

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