Release of vitamin B₁₂—binding protein by human leukocytes in vitro

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Abstract

Human granulocytes (G) contain a vitamin B12-binding protein (B12BP). There is evidence that chronic myelogenous leukemia leukocytes (CMLL) may synthesize B12BP. Our prior studies suggested that intact, living intravascular G synthesize and release such protein into extracellular compartments in vivo.

Authors

José Corcino, Stephen Krauss, Samuel Waxman, Victor Herbert