Notch expression patterns in the retina: an eye on receptor–ligand distribution during angiogenesis
JJ Hofmann, ML Iruela-Arispe - Gene Expression Patterns, 2007 - Elsevier
The critical contribution of the Notch signaling pathway to vascular morphogenesis has been
underscored by loss-of-function studies in mouse and zebrafish. Nonetheless, a
comprehensive understanding as to how this signaling system influences the formation of
blood vessels at the cellular and molecular level is far from reached. Here, we provide a
detailed analysis of the distribution of active Notch1 in relation to its DSL (Delta, Serrate,
Lag2) ligands, Jagged1, Delta-like1, and Delta-like4, during progressive stages of vascular …
underscored by loss-of-function studies in mouse and zebrafish. Nonetheless, a
comprehensive understanding as to how this signaling system influences the formation of
blood vessels at the cellular and molecular level is far from reached. Here, we provide a
detailed analysis of the distribution of active Notch1 in relation to its DSL (Delta, Serrate,
Lag2) ligands, Jagged1, Delta-like1, and Delta-like4, during progressive stages of vascular …