The role of the carboxyl ester lipase (CEL) gene in pancreatic disease
BB Johansson, K Fjeld, K El Jellas, A Gravdal, M Dalva… - Pancreatology, 2018 - Elsevier
The enzyme carboxyl ester lipase (CEL), also known as bile salt-dependent or-stimulated
lipase (BSDL, BSSL), hydrolyzes dietary fat, cholesteryl esters and fat-soluble vitamins in the
duodenum. CEL is mainly expressed in pancreatic acinar cells and lactating mammary
glands. The human CEL gene resides on chromosome 9q34. 3 and contains a variable
number of tandem repeats (VNTR) region that encodes a mucin-like protein tail. Although
the number of normal repeats does not appear to significantly influence the risk for …
lipase (BSDL, BSSL), hydrolyzes dietary fat, cholesteryl esters and fat-soluble vitamins in the
duodenum. CEL is mainly expressed in pancreatic acinar cells and lactating mammary
glands. The human CEL gene resides on chromosome 9q34. 3 and contains a variable
number of tandem repeats (VNTR) region that encodes a mucin-like protein tail. Although
the number of normal repeats does not appear to significantly influence the risk for …
