Epidermolysis bullosa and the risk of life-threatening cancers: the National EB Registry experience, 1986-2006
JD Fine, LB Johnson, M Weiner, KP Li… - Journal of the American …, 2009 - Elsevier
BACKGROUND: Case series have demonstrated that potentially lethal cutaneous
squamous cell carcinomas arise in patients with recessive dystrophic epidermolysis bullosa
(RDEB), although the magnitude of this risk is undefined. METHODS: Systematic case
finding and data collection were performed throughout the continental United States (1986-
2002) by the National EB Registry on 3280 EB patients to determine cumulative and
conditional risks for squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and …
squamous cell carcinomas arise in patients with recessive dystrophic epidermolysis bullosa
(RDEB), although the magnitude of this risk is undefined. METHODS: Systematic case
finding and data collection were performed throughout the continental United States (1986-
2002) by the National EB Registry on 3280 EB patients to determine cumulative and
conditional risks for squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and …