A previously unreported property of human mononuclear phagocytes is the ability of these
cells to spontaneously aggregate. Fresh mononuclear cells obtained after plateletpheresis
were noted to spontaneously form large cellular aggregates. Dual parameter
immunofluorescence analysis demonstrated that the aggregating cells were positive for the
monocyte marker CD11 (complement receptor, type 3) but were negative for the lymphocyte
marker CD3 (T3 antigen). In addition, less than 5% of the nonaggregating cells were CD11+ …